Keywords: dengue

Wolbachia as translational science: controlling mosquito-borne pathogens

E. P. Caragata, H. L. C. Dutra, P. H. F. Sucupira, A. G. A. Ferreira and L. A. Moreira,  Trends in Parasitology,  2021.
In this review we examine how exploiting the Wolbachia?mosquito relationship has become an increasingly popular strategy for controlling arbovirus transmission. Field deployments of Wolbachia-infected mosquitoes have led to significant decreases in dengue virus incidence via high ...
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Yes, genetically modified mosquitoes do exist, but they don’t bite and aren’t harmful to humans

E. Jones and M. Chamberlin,  WKYC Studios,  2021.
In 2021, Oxitec, a biotechnology company that develops genetically modified insects that safely and sustainably control pests that spread disease, damage crops and harm livestock across the globe, partnered with the Florida Keys Mosquito Control District (FKMCD) to evaluate the ...
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Combating mosquito-borne diseases using genetic control technologies

G.-H. Wang, S. Gamez, R. R. Raban, J. M. Marshall, L. Alphey, M. Li, J. L. Rasgon and O. S. Akbari,  Nature Communications,  12:4388. 2021.
Mosquito-borne diseases, such as dengue and malaria, pose significant global health burdens. Unfortunately, current control methods based on insecticides and environmental maintenance have fallen short of eliminating the disease burden. Scalable, deployable, genetic-based ...
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Fighting disease: How are genetically engineered mosquitoes regulated?

A. Julie,  Global News,  2021.
Mosquitoes have long been associated with the spread of diseases like malaria, dengue fever and the Zika virus. But scientists around the world have been exploring the possibility that mosquitoes could also be key to slowing the spread of disease. By genetically altering the DNA ...
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The (Losing) Battle Against Mosquitoes In Texas

J. Clayton,  Texas Public Radio,  2021.
Jerry Clayton: Mosquitoes are a fact of life in Texas, and the battle against the pesky biting insects is never ending. But there are some new weapons on the horizon. Zach Adleman is an associate professor of entomology at Texas A&M University. He joins us today. Thanks for being ...
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A wAlbB Wolbachia&lt transinfection displays stable phenotypic effects across divergent Aedes aegypti mosquito backgrounds

P. A. Ross, X. Gu, K. L. Robinson, Q. Yang, E. Cottingham, Y. Zhang, H. L. Yeap, X. Xu, N. M. Endersby-Harshman and A. A. Hoffmann,  bioRxiv,  2021.06.25.450002. 2021.
Aedes mosquitoes harboring intracellular Wolbachia bacteria are being released in arbovirus and mosquito control programs. With releases taking place around the world, understanding the contribution of host variation to Wolbachia phenotype is crucial. We generated a Wolbachia ...
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Manipulated Mosquitoes Cut Dengue by 77%

T. Hayes,  Healthcare Packaging,  2021.
Dengue, a mosquito-borne viral disease, wasn’t that common 50 years ago. In fact, only nine countries had severe outbreaks. But since then, it’s been on a steady incline to the point that there are now 400 million infections a year that contribute to 22,000 deaths. ...
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Dengue fever: Upstaged but not outmatched by COVID-19

C. E. Baclig,  INQUIRER.NET,  2021.
Science has made gains in the war on dengue and other diseases that mosquitoes carry, like malaria.One of these is the World Mosquito Program (WMP), a non-profit initiative that aims to protect the global community from mosquito-borne viral diseases, by deploying a natural ...
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Genetically Modified Mosquitoes; ‘Truth Like Oil’ Novel

Here and Now,  WBUR,  2021.
Florida Keys officials are working on a unique experiment: hatching thousands of genetically modified mosquitos and releasing them. Andrea Leal of the Florida Keys Mosquito Control District explains.
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Dengue Infections Can Be Sharply Reduced With Wolbachia Bacteria

J. Stone,  Medscape,  2021.
A modestly titled new study released in the New England Journal of Medicine belies the extraordinary 77% protective efficacy reported for preventing dengue infections with Wolbachia-infected Aedes aegypti mosquitoes. A cluster-randomized clinical trial, the AWED ("Applying ...
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Making mosquitoes to fight mosquitoes to prevent dengue

A. George,  Times of India,  2021.
In 2017, Delhi Chief Minister Arvind Kejriwal tweeted that the national capitl needed to be made mosquito-free. The same year, his Kerala counterpart, Pinaray Vijayan, called a three-day state-wide cleanliness drive as hospitals filled with genue patients.
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Dengue Fever Cut Down by 77% With Groundbreaking Bacteria-Armed Mosquitoes

M. Davis,  The Science Times,  2021.
Scientists found that dengue fever cases have decreased by 77% in a groundbreaking trial that took place in Yogyakarta City, Indonesia. They used Wolbachia-infected mosquitoes that reduced their ability to spread the dengue fever. The team at the World Mosquito Program said that ...
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Mosquito ‘bacteria hack’ nearly eliminates dengue fever and could save millions of lives

A. Wilkins,  METRO,  2021.
Mosquitoes infected with a ‘miraculous’ bacteria have been shown to reduce dengue fever cases by 77%, in a groundbreaking new study. Scientists released mosquitoes infected with ‘Wolbachia’ bacteria into the Indonesian city of Yogyakarta – but only in certain zones. In ...
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‘Miraculous’ mosquito hack cuts dengue by 77%

J. Gallagher,  BBC,  2021.
Dengue fever cases have been cut by 77% in a "groundbreaking" trial that manipulates the mosquitoes that spread it, say scientists. They used mosquitoes infected with "miraculous" bacteria that reduce the insect's ability to spread dengue. The trial took place in Yogyakarta city, ...
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Modified mosquitoes reduce dengue cases by 77% in Indonesia experiment

M. Fox,  CNN,  2021.
An experiment to infect mosquitoes with bacteria that stop them from transmitting viruses appears to have helped reduced the spread of deadly dengue virus in Indonesia, researchers reported Wednesday. The modified mosquitoes thrived for three years, and cases of dengue were ...
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Efficacy of Wolbachia-Infected Mosquito Deployments for the Control of Dengue

A. Utarini, C. Indriani, R. A. Ahmad, W. Tantowijoyo, E. Arguni, M. R. Ansari, E. Supriyati, D. S. Wardana, Y. Meitika, I. Ernesia, I. Nurhayati, E. Prabowo, B. Andari, B. R. Green, L. Hodgson, Z. Cutcher, E. Rancès, P. A. Ryan, S. L. O’Neill, S. M. Dufau,  New England Journal of Medicine,  384:2177-2186. 2021.
BACKGROUND Aedes aegypti mosquitoes infected with the wMel strain of Wolbachia pipientis are less susceptible than wild-type A. aegypti to dengue virus infection. METHODS We conducted a cluster-randomized trial involving releases of wMel-infected A. aegypti mosquitoes for the ...
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A Pivotal Mosquito Experiment Could Not Have Gone Better

E. Yong,  The Atlantic,  2021.
The World Mosquito Program (WMP), a nonprofit that pioneered this technique, had run small pilot studies in Australia that suggested it could work. Utarini, who co-leads WMP Yogyakarta, has now shown conclusively that it does. Her team released Wolbachia-carrying mosquitoes in ...
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Mosquitoes armed with virus-fighting bacteria sharply curb dengue infections, hospitalizations

K. Servick,  Science,  2021.
A strategy for fighting dengue fever with bacteria-armed mosquitoes has passed its most rigorous test yet: a large, randomized, controlled trial. Researchers reported today dramatic reductions in rates of dengue infection and hospitalization in areas of an Indonesian city where ...
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Study demonstrates ‘exciting potential’ of Wolbachia-infected mosquitoes to control dengue

G. Gallagher,  Healio,  2021.
The release of Wolbachia-infected mosquitoes led to a 77% reduction in the incidence of symptomatic dengue in an Indonesian city, according to researchers, who said the same approach could be used to fight other mosquito-borne diseases. The study tested a strain of Wolbachia ...
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Bill Gates Releasing Genetically Modified Mosquitoes in Florida? Here’s the Whole Story

M. Dapcevich,  Snopes,  2021.
Bill Gates is not himself releasing mosquitoes into the wild. However, the Bill and Melinda Gates Foundation did award grants that funded biotech company Oxitec's work to develop genetically modified mosquitoes that may help reduce the spread of malaria and other mosquito-borne ...
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Mutant mosquitoes carrying ‘death gene’ released as ‘bio-engineered’ insects terrify

J. Caven,  Daily Star,  2021.
Mutant mosquitoes which carry a ‘death gene’ have been released into the skies in a bid to curb diseases from spreading to humans. Tens of thousands of genetically modified male insects will mate with female Aedes aegypti mosquitoes, which transmit illnesses, in Florida ...
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‘Death gene’ in genetically modified male mosquitoes

J. Goddard,  The Times,  2021.
Tens of thousands of bio-engineered mosquitoes have taken flight in the Florida Keys under a pilot project that aims to breed insects programmed with a “death switch”. Genetically modified males produced by Oxitec — a British-founded biotechnology company — have begun ...
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Mosquitoes are deadly pests, genetically-modified mosquitoes could help stop disease

T. Browne,  ClickOrlando,  2021.
Hearing the words “genetically modified mosquitoes” can sound like the plot for a science-fiction movie but Meredith Fenson, a native Floridian turned biological pest control specialist says, “mosquitoes are the world’s deadliest animal by far” and a study happening ...
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Florida Environmental Group Says GMO Mosquitoes Fall Short on Scientific Rigor

C. Drukier,  NTD,  2021.
America’s first genetically modified mosquitoes are now buzzing around six locations in the Florida Keys as part of a pilot project. Developed by UK biotech company Oxitec, the bugs are designed to kill off the wild population of Aedes aegypti mosquitoes that carry diseases ...
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Genetically Modified Mosquitoes Take Flight to Fight Invasive Species in Florid

T. Machemer,  Smithosonian Magazine,  2021.
In late April, the biotechnology company Oxitec placed blue-and-white hexagonal boxes on the properties of six private volunteers around the Florida Keys. After pouring in water, the genetically modified mosquito eggs inside activated and hatched. Now the first larvae have ...
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Genetically modified mosquitoes may help scientists swat dreaded midge

W. Jean,  The Times,  2021.
Scotland’s bloodthirsty midges may finally meet their match thanks to revolutionary genetic manipulation techniques that could stop the pesky insects biting chunks out of the tourist industry. News that a British biotechnology company has created genetically modified non-biting ...
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First Genetically Modified Mosquitoes Released in U.S. Are Hatching Now

D. Coffey,  Scientific American,  2021.
This week, mosquito eggs placed in the Florida Keys are expected to hatch tens of thousands of genetically modified mosquitoes, a result of the first U.S. release of such insects in the wild. A biotechnology firm called Oxitec delivered the eggs in late April as part of a ...
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In a World-First, Genetically Modified Mosquitoes Are Hatching in the US

B. Bergan,  INTERSTING ENGINEERING,  2021.
Mosquito eggs placed in the Florida Keys are about to hatch tens of thousands of genetically altered mosquitos, the first such release of "synthetic" insects in the world, according to an initial report from Scientific American. Pilot program for genetically modified mosquitoes ...
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The U.S.’s first open-air genetically modified mosquitoes have taken flight

S. Milius,  Science News,  2021.
The first genetically modified mosquitoes that will be allowed to fly free outdoors in the United States have started reaching the age for mating in the Florida Keys. In a test of the biotech company Oxitec’s GM male mosquitoes for pest control, these Aedes aegypti started ...
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Use of genetically modifed mosquitoes to minimize the burden of diseases casused by mosquitoes in South Texas.

MDN Staff,  MegaDoctor News,  2021.
Of the many species of mosquitoes, female Aedes aegypti is the primary vector that is responsible for transmission of several diseases and has been most extensively studied. The efforts of the World Health Organization and the Center for Disease Control and Prevention to prevent ...
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Monster Mosquito–Why the Technology of Genetically Modified Mosquitoes is Dangerous and Should Be Stopped Worldwide

B. Dogra,  counter currents,  2021.
After sparking controversy in other countries including India, the technology of genetically engineered mosquitoes is now leading to widespread protests in Florida USA. Here the biotechnology giant company Oxitec in collaboration with local officialdom is moving ahead with a ...
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Florida releases genetically modified mosquitoes in hopes to reduce spread of disease

A. Fahim,  Reuters,  2021.
Genetically modified mosquitoes have been released for the first time in the United States, taking flight in the Florida Keys in a pilot program intended to reduce the spread of deadly diseases such as dengue, yellow fever and the Zika virus.After an odyssey spanning more than a ...
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Why Florida is releasing genetically modified mosquitoes

M. Murphy,  The Telegraph,  2021.
The thousands of lab-grown mosquitoes hatching in humid gardens across Florida’s tropical Key West next week will be blissfully ignorant of the controversy they have caused. Billboards have already begun appearing near busy motorways in protest of their arrival, with one ...
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Genetically Modified Mosquitoes Have Come to the U.S. Will They Work?

A. de la Garza,  TIME,  2021.
“Our Mosquito Project Takes Flight,” reads a baby-blue billboard off US-1 in the Florida Keys, alongside an image of an insect tracing a path in the shape of a heart. Sponsored by the local mosquito control board and U.K.-based biotech firm Oxitec, the ad promotes a ...
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Bill Gates finances the creation of transgenic mosquitoes

Explica.co,  explica,  2021.
Male mosquitoes (they do not bite. They feed on nectar, not blood) from Oxitec will emerge from release boxes placed in six locations in the Florida Keys to mate with local female mosquitoes (they do bite. They do feed on blood). The female offspring from these encounters cannot ...
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Genetically Modified Mosquitoes Released In US For First Time To Combat Disease

J. Van Zijl,  IFL Science,  2021.
A landmark project, spearheaded by the biotechnology company, Oxitec, has released genetically modified mosquitos in the Florida Keys. This marks the first time that genetically modified mosquitos have been released into the wild in the US. The reason: to combat the Aedes aegypti ...
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Genetically Modified Mosquitoes Released In Florida ‘Jurassic Park Experiment’

D. Richardson,  UNILAD,  2021.
Mosquitos are not only annoying but they can carry disease in their bites. In response to this, a company called Oxitec has genetically modified male mosquitos to pass on a killswitch to females. It is hoped that these genetically modified pests will help stop the transmission of ...
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Gravitas: Genetically modified mosquitoes arrive in Florida

P. Sharma,  WION,  2021.
Genetically engineered mosquitoes have arrived in U.S. 20 million 'modified mosquitoes' will be released in Florida to help prevent Dengue. But, Florida residents fear a 'mosquito apocalypse'
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Reengineered mosquitoes released in Florida pilot program

S. W. Tan,  The Washington Times,  2021.