Scholarly Literature
This is an aggregation of scholarly literature from peer-reviewed journals, bioRxiv , medRxiv and arXiv preprint servers focused on natural and engineered selfish genetic elements and genetic biocontrol. New citations are added as they appear. This content is intended for anyone interested in the scholarly literature on gene drive and genetic biocontrol.
Preferential accumulation of sex and Bs chromosomes in biarmed karyotypes by meiotic drive and rates of chromosomal changes in fishes
Tags: Chromosomal drive, Evolution, FishMolina, WFM, P. A.; Bertollo, L. A. C.; Bidau, C. J., Anais Da Academia Brasileira De Ciencias, 86:1801-1812. 2014.
Mechanisms of accumulation based on typical centromeric drive or of chromosomes carrying pericentric inversions are adjusted to the general karyotype differentiation in the principal Actinopterygii orders. Here, we show that meiotic drive in fish is also supported by preferential ...
Medusa: A novel gene drive system for confined suppression of insect populations
Tags: Other arthropods, Toxin-antidoteMarshall, JMH, B. A., PLOS One, 9:e102694. 2014.
Gene drive systems provide novel opportunities for insect population suppression by driving genes that confer a fitness cost into pest or disease vector populations; however regulatory issues arise when genes are capable of spreading across international borders. Gene drive ...
The organization and evolution of the Responder satellite in species of the Drosophila melanogaster group: dynamic evolution of a target of meiotic drive
Tags: Evolution, Gene drive mechanisms, Other arthropods, Transmission distortionLarracuente, AM, BMC Evolutionary Biology, 14:233. 2014.
: Satellite DNA can make up a substantial fraction of eukaryotic genomes and has roles in genome structure and chromosome segregation. The rapid evolution of satellite DNA can contribute to genomic instability and genetic incompatibilities between species. Despite its ubiquity ...
Evolution and biology of supernumerary B chromosomes
Tags: Evolution, X chromosome, Y-chromosomeHouben, AB-M, A. M.; Klemme, S.; Timmis, J. N., Cellular and Molecular Life Sciences, 71:467-478. 2014.
B chromosomes (Bs) are dispensable components of the genome exhibiting non-Mendelian inheritance and have been widely reported on over several thousand eukaryotes, but still remain an evolutionary mystery ever since their first discovery over a century ago [1]. Recent advances in ...
The Trojan female technique: a novel, effective and humane approach for pest population control
Tags: Gene drive synthetic, Sex distorter, Sterile insect technique (SIT)N. J. Gemmell, A. Jalilzadeh, R. K. Didham, T. Soboleva and D. M. Tompkins, Proceedings of the Royal Society B: Biological Sciences, 280:20132549. 2013.
We use mathematical models to test a new twist on the SMT, using maternally inherited mitochondrial (mtDNA) mutations that affect male, but not female reproductive fitness. ‘Trojan females’ carrying suchmutations, and their female descendants, produce ...
Swarming and mating behavior of male Anopheles arabiensis Patton (Diptera: Culicidae) in an area of the Sterile Insect Technique Project in Dongola, northern Sudan
Tags: Africa, Anopheles, Sterile insect technique (SIT)M. M. Hassan, H. M. Zain, M. A. Basheer, H. E. F. Elhaj and B. B. El-Sayed, Acta Tropica, 132:S64-S69. 2013.
The problems facing the conventional mosquito control methods including resistance to insecticides have led to the development of alternative methods such as the Sterile Insect Technique (SIT) to suppress populations of the malaria vector Anopheles arabiensis in northern Sudan. ...
Global existence and asymptotic behavior of a model for biological control of invasive species via supermale introduction
Tags: Genetic biocontrol, Modeling, Sex distorterR. D. Parshad, S. Kouachi and J. B. Gutierrez, Communications in Mathematical Sciences, 11:971-992. 2013.
The purpose of this manuscript is to propose a model for the biological control of invasive species, via introduction of phenotypically modified organisms into a target population. We are inspired by the earlier Trojan Y Chromosome model [J.B. Gutierrez, J.L. Teem, J. Theo. Bio., ...
Demographic effects on the use of genetic options for the control of mosquitofish, Gambusia holbrooki
Tags: Genetic biocontrol, Modeling, Pest management, Population genetics/dynamics, Sex distorter, Sterile insect technique (SIT)R. E. Thresher, M. Canning and N. J. Bax, Ecological Applications, 23:801-814. 2013.
This study tests the sensitivity of genetically based pest control options based on sex ratio distortion to intra-and intersexual aggressive interactions that affect male and female survival and fitness. Data on these interactions and their impacts were gathered for the ...
Analysis of the Trojan Y-Chromosome eradication strategy for an invasive species
Tags: Fish, Genetic biocontrol, Modeling, Sex distorterX. Y. Wang, J. R. Walton, R. D. Parshad, K. Storey and M. Boggess, Journal of Mathematical Biology, 68:1731-1756. 2013.
The Trojan Y-Chromosome (TYC) strategy, an autocidal genetic biocontrol method, has been proposed to eliminate invasive alien species. In this work, we analyze the dynamical system model of the TYC strategy, with the aim of studying the viability of the TYC eradication and ...
Combining the Trojan Y chromosome and daughterless carp eradication strategies
Tags: Fish, Genetic biocontrol, Invasive species, Sex distorterJ. L. Teem and J. B. Gutierrez, Biological Invasions, 16:1231-1240. 2013.
The Trojan Y chromosome (TYC) strategy and the daughterless carp (DC) strategy represent two autocidal genetic biocontrol methods for eliminating invasive fish by changing the sex ratio of the population. Each strategy is designed to reduce the number of females in a target ...
A comparison of the Trojan Y Chromosome and daughterless carp eradication strategies
Tags: Fish, Genetic biocontrol, Invasive species, Sex distorterJ. L. Teem, J. B. Gutierrez and R. D. Parshad, 16, 16:1217-1230. 2013.
Two autocidal genetic biocontrol methods have been proposed as a means to eliminate invasive fish by changing the sex ratio of the population: the Trojan Y Chromosome (TYC) strategy and the Daughterless Carp (DC) strategy. Both strategies were modeled using ordinary differential ...
Elimination of Y chromosome-bearing spermatids during spermiogenesis in an autosomal sex-ratio mutant of Drosophila simulans
Tags: Gene drive mechanisms, Other arthropods, X chromosomeYasuno, YI, Y. H.; Yamamoto, M. T., Genes & Genetic Systems, 88:113-126. 2013.
Sex ratio distortion, which is commonly abbreviated as sex-ratio, has been studied in many Drosophila species, but the mechanism remains largely unknown. Here, we report on the sex-ratio mutant of D. simulans named excess of females (exf). The third chromosomal recessive mutation ...
Engineering synthetic medea-based and threshold- dependent underdominance-based gene drive systems in mosquitoes
Tags: Gene drive syntheticAkbari, OM, J.; Antoshechkin, I.; Matzen, K.; Papathanos, P.; Kennedy, K.; Ward, C.; Chen, C. H.; Guo, M.; Hay, B., Pathogens and Global Health, 107:442-442. 2013.
Mosquito population replacement requires gene drive mechanisms in order to spread linked genes, mediating disease refractoriness, through wild populations. Medea is predicted to be a low threshold gene drive mechanism, able to spread from low initial frequency. Such a system is ...
Sex-biased gene expression during head development in a sexually dimorphic stalk-eyed fly
Tags: Gene drive mechanismsWilkinson, GSJ, P. M.; Metheny, J. D.; Baker, R. H., PLOS One, 8:1-10. 2013.
Stalk-eyed flies (family Diopsidae) are a model system for studying sexual selection due to the elongated and sexually dimorphic eye-stalks found in many species. These flies are of additional interest because their X chromosome is derived largely from an autosomal arm in other ...
The dynamic relationship between polyandry and selfish genetic elements
Tags: Ecology, EvolutionWedell, N, Philosophical Transactions of the Royal Society B-Biological Sciences, 368:10. 2013.
Selfish genetic elements (SGEs) are ubiquitous in eukaryotes and bacteria, and make up a large part of the genome. They frequently target sperm to increase their transmission success, but these manipulations are often associated with reduced male fertility. Low fertility of ...
Meiotic drive in mice carrying t-complex in their genome
Tags: Evolution, Rodents, Transmission distortionSafronova, LDC, V. L., Russian Journal of Genetics, 49:885-897. 2013.
The deviation of alleles and chromosomes from Mendelian inheritance is characteristic of the meiotic drive. This review describes the mechanism in question using the best-studied example of transmitted ratio distortion in the heterozygous male mice carrying t-haplotypes. The ...
Association of polyandry and sex-ratio drive prevalence in natural populations of Drosophila neotestacea
Tags: Gene drive mechanisms, Transmission distortionPinzone, CAD, K. A., Proceedings of the Royal Society B-Biological Sciences, 280:20131397. 2013.
Selfish genetic elements bias their own transmission to the next generation, even at the expense of the fitness of their carrier. Sex-ratio (SR) meiotic drive occurs when an X-chromosome causes Y-bearing sperm to die during male spermatogenesis, so that it is passed on to all of ...
Transmission rate variation among three B chromosome variants in the fish Prochilodus lineatus (Characiformes, Prochilodontidae)
Tags: Chromosomal drive, Evolution, Gene drive mechanismsPenitente, MV, T. A.; Senhorini, J. A.; Bortolozzi, J.; Foresti, F.; Porto-Foresti, F., Anais Da Academia Brasileira De Ciencias, 85:1371-1377. 2013.
Cytogenetic studies were developed in Prochilodus lineatus (Valenciennes 1836), describing an interesting system of small supernumerary chromosomes. The purpose of this work is to study the frequency and morphology of B chromosomes in individuals from the parental line and the ...
Modelling the spatial spread of a homing endonuclease gene in a mosquito population
Tags: Anopheles, Field trials, Gene drive synthetic, Malaria, Other arthropods, Replicator/site directed nuclease, ResistanceNorth, AB, A.; Godfray, H. C. J., Journal of Applied Ecology, 50:1216-1225. 2013.
Homing endonuclease genes (HEGs) exist naturally in many single-celled organisms and can show extremely strong genetic drive allowing them to spread through populations into which they are introduced. They are being investigated as tools to manipulate the populations of important ...
Spread of a new parasitic B chromosome variant is facilitated by high gene flow
Tags: Chromosomal drive, Ecology, Evolution, Other arthropodsManrique-Poyato, MIL-L, M. D.; Cabrero, J.; Perfectti, F.; Camacho, J. P. M., PLOS One, 8:e83712. 2013.
The B-24 chromosome variant emerged several decades ago in a Spanish population of the grasshopper Eyprepocnemis plorans and is currently reaching adjacent populations. Here we report, for the first time, how a parasitic B chromosome (a strictly vertically transmitted parasite) ...
Modeling the dynamics of a non-limited and a self-limited gene drive system in structured Aedes aegypti populations
Tags: Gene drive mechanisms, Gene drive synthetic, Other arthropods, UnderdominanceLegros, MX, C. G.; Morrison, A.; Scott, T. W.; Lloyd, A. L.; Gould, F., PLOS One, 8:e83354. 2013.
Recently there have been significant advances in research on genetic strategies to control populations of disease-vectoring insects. Some of these strategies use the gene drive properties of selfish genetic elements to spread physically linked anti-pathogen genes into local ...
Diversity and abundance of the abnormal chromosome 10 meiotic drive complex in Zea mays
Tags: Evolution, Transmission distortionKanizay, LBP, T.; Lowry, E. G.; Hufford, M. B.; Peterson, D. G.; Ross-Ibarra, J.; Dawe, R. K., Heredity, 110:570-577. 2013.
Maize Abnormal chromosome 10 (Ab10) contains a classic meiotic drive system that exploits the asymmetry of meiosis to preferentially transmit itself and other chromosomes containing specialized heterochromatic regions called knobs. The structure and diversity of the Ab10 meiotic ...
Transmission ratio distortion: review of concept and implications for genetic association studies
Tags: Gene drive mechanismsHuang, LOL, A.; Infante-Rivard, C., Human Genetics, 132:245-263. 2013.
Transmission ratio distortion (TRD) occurs when one of the two alleles from either parent is preferentially transmitted to the offspring. This leads to a statistical departure from the Mendelian law of inheritance, which states that each of the two parental alleles is transmitted ...
Mutations to the piRNA Pathway Component Aubergine Enhance Meiotic Drive of Segregation Distorter in Drosophila melanogaster
Tags: Gene drive mechanisms, Other arthropods, Transmission distortionGell, SLR, R. A., Genetics, 193:771-784. 2013.
Diploid sexual reproduction involves segregation of allelic pairs, ensuring equal representation of genotypes in the gamete pool. Some genes, however, are able to "cheat" the system by promoting their own transmission. The Segregation distorter (Sd) locus in Drosophila ...
Guidance on the environmental risk assessment of genetically modified animals.
Tags: Ethics, Policy, Regulation, Risk and safetyEFSA GMO Panel (EFSA Panel on Genetically Modified Organisms), EFSA Journal, 11:3200. 2013.
This document provides guidance for the environmental risk assessment (ERA) of living genetically modified (GM) animals, namely fish, insects and mammals and birds, to be placed on the European Union (EU) market in accordance with Regulation (EC) No 1829/2003 or Directive ...
Mechanism of meiotic drive in mammals
Tags: Other mammals, Transmission distortionChmatal, LF, K.; Schultz, R. M.; Lampson, M. A., Molecular Biology of the Cell, 24:3775. 2013.
Meiotic drive is a phenomenon responsible for an unequal representation of alleles or whole chromosomes among gametes as a result of the mechanics of meiotic division (Sandler et Novitski 1957). When it drives segregation of Robertsonian translocations (Rb), a common chromosomal ...
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
Tags: Gene drive mechanisms, Gene drive synthetic, Other arthropods, Replicator/site directed nucleaseChan, YST, R.; Jarjour, J.; Huen, D. S.; Stoddard, B. L.; Russell, S., PLOS One, 8:e74254. 2013.
The homing endonuclease gene (HEG) drive system, a promising genetic approach for controlling arthropod populations, utilises engineered nucleases to spread deleterious mutations that inactivate individual genes throughout a target population. Previous work with a naturally ...
Optimising homing endonuclease gene drive performance in a semi-refractory species: The Drosophila melanogaster experience
Tags: Gene drive mechanisms, Gene drive synthetic, Other arthropods, Replicator/site directed nucleaseChan, YSH, D. S.; Glauert, R.; Whiteway, E.; Russell, S., PLOS One, 8:e54130. 2013.
Homing endonuclease gene (HEG) drive is a promising insect population control technique that employs meganucleases to impair the fitness of pest populations. Our previous studies showed that HEG drive was more difficult to achieve in Drosophila melanogaster than Anopheles gambiae ...
Natural variation of the Y chromosome suppresses sex ratio distortion and modulates testis-specific gene expression in Drosophila simulans
Tags: Evolution, Gene drive mechanisms, Other arthropods, X chromosomeBranco, ATT, Y.; Hartl, D. L.; Lemos, B., Heredity, 111:8-15. 2013.
X-linked sex-ratio distorters that disrupt spermatogenesis can cause a deficiency in functional Y-bearing sperm and a female-biased sex ratio. Y-linked modifiers that restore a normal sex ratio might be abundant and favored when a X-linked distorter is present. Here we ...
Local dynamics of a fast-evolving sex-ratio system in Drosophila simulans
Tags: Ecology, Evolution, Gene drive mechanisms, Other arthropods, X chromosomeBastide, HG, P. R.; Ogereau, D.; Cazemajor, M.; Montchamp-Moreau, C., Molecular Ecology, 22:5352-5367. 2013.
By distorting Mendelian transmission to their own advantage, X-linked meiotic drive elements can rapidly spread in natural populations, generating a sex-ratio bias. One expected consequence is the triggering of a co-evolutionary arms race between the sex chromosome that carries ...
Germline excision of transgenes in Aedes aegypti by homing endonucleases
Tags: Gene drive synthetic, Other arthropods, Replicator/site directed nucleaseAryan, AA, M. A. E.; Myles, K. M.; Adelman, Z. N., Scientific Reports, 3:1603. 2013.
Aedes (Ae.) aegypti is the primary vector for dengue viruses (serotypes1-4) and chikungunya virus. Homing endonucleases (HEs) are ancient selfish elements that catalyze double-stranded DNA breaks (DSB) in a highly specific manner. In this report, we show that the HEs Y2-I-AniI, ...
A Synthetic Gene Drive System for Local, Reversible Modification and Suppression of Insect Populations
Tags: Gene drive synthetic, Other arthropods, UnderdominanceAkbari, OSM, K. D.; Marshall, J. M.; Huang, H. X.; Ward, C. M.; Hay, B. A., Current Biology, 23:671-677. 2013.
Replacement of wild insect populations with genetically modified individuals unable to transmit disease provides a self-perpetuating method of disease prevention but requires a gene drive mechanism to spread these traits to high frequency [1-3]. Drive mechanisms requiring that ...
Ethical issues in field trials of genetically modified disease-resistant mosquitoes
Tags: Ethics, Field trials, Gene drive synthetic, Genetically modified mosquitoes, Malaria, Policy, Risk and safetyD. B. Resnik, Developing World Bioethics, 14:37-46. 2012.
Mosquito-borne diseases take a tremendous toll on human populations, especially in developing nations. In the last decade, scientists have developed mosquitoes that have been genetically modified to prevent transmission of mosquito-borne diseases, and field trials have been ...
The contribution of female meiotic drive to the evolution of neo-sex chromosomes
Tags: Evolution, Gene drive mechanisms, Transmission distortionYoshida, KK, J., Evolution, 66:3198-3208. 2012.
Sex chromosomes undergo rapid turnover in certain taxonomic groups. One of the mechanisms of sex chromosome turnover involves fusions between sex chromosomes and autosomes. Sexual antagonism, heterozygote advantage, and genetic drift have been proposed as the drivers for the ...
From genes to games: Cooperation and cyclic dominance in meiotic drive
Tags: Evolution, Gene drive mechanisms, Transmission distortionTraulsen, AR, F. A., Journal of Theoretical Biology, 299:120-125. 2012.
Evolutionary change can be described on a genotypic level or a phenotypic level. Evolutionary game theory is typically thought of as a phenotypic approach, although it is frequently argued that it can also be used to describe population genetic evolution. Interpreting the ...
Genetic mapping a meiotic driver that causes sex ratio distortion in the mosquito Aedes aegypti
Tags: Gene drive mechanisms, Other arthropodsShin, DM, A.; Severson, D. W., Journal of Heredity, 103:303-307. 2012.
An endogenous meiotic driver in the dengue and yellow fever vector mosquito Aedes aegypti can cause highly male-biased sex ratio distortion in crosses from suitable genetic backgrounds. We previously selected a strain that carries a strong meiotic drive gene (D) linked with the ...
No evidence of mate discrimination against males carrying a sex ratio distorter in Drosophila pseudoobscura
Tags: Evolution, Gene drive mechanisms, Transmission distortionPrice, TARL, Z.; Smith, D. T.; Hurst, G. D. D.; Wedell, N., Behavioral Ecology and Sociobiology, 66:561-568. 2012.
Selfish genetic elements (SGEs) that spread by manipulating spermatogenesis often have highly deleterious effects on males that carry them. Females that mate with male carriers of SGEs can also suffer significant costs: they receive fewer and poorer-quality sperm, their offspring ...
Evaluating the evidence for transmission distortion in human pedigrees
Tags: Gene drive mechanisms, Other mammals, Transmission distortionMeyer, WKA, B.; Ober, C.; Ebner, T.; Tiemann-Boege, I.; Hudson, R. R.; Przeworski, M., Genetics, 191:215-232. 2012.
Children of a heterozygous parent are expected to carry either allele with equal probability. Exceptions can occur, however, due to meiotic drive, competition among gametes, or viability selection, which we collectively term "transmission distortion" (TD). Although there are ...
Confinement of gene drive systems to local populations: A comparative analysis
Tags: Gene drive, Other arthropods, Toxin-antidote, UnderdominanceMarshall, JMH, B. A., Journal of Theoretical Biology, 294:153-171. 2012.
Mosquito-borne diseases such as malaria and dengue fever pose a major health problem through much of the world. One approach to disease prevention involves the use of selfish genetic elements to drive disease-refractory genes into wild mosquito populations. Recently engineered ...
General principles of single-construct chromosomal gene drive
Tags: Ecology, Toxin-antidoteMarshall, JMH, B. A., Evolution, 66:2150-2166. 2012.
Gene drive systems are genetic elements capable of spreading into a population even if they confer a fitness cost to their host. We consider a class of drive systems consisting of a chromosomally located, linked cluster of genes, the presence of which renders specific classes of ...
The Selfish Segregation Distorter Gene Complex of Drosophila melanogaster
Tags: Evolution, Gene drive mechanisms, Other arthropods, Transmission distortionLarracuente, AMP, D. C., Genetics, 192:33-53. 2012.
Segregation Distorter (SD) is an autosomal meiotic drive gene complex found worldwide in natural populations of Drosophila melanogaster. During spermatogenesis, SD induces dysfunction of SD+ spermatids so that SD/SD+ males sire almost exclusively SD-bearing progeny rather than ...
Complex genetic nature of sex-independent transmission ratio distortion in Asian rice species: the involvement of unlinked modifiers and sex-specific mechanisms
Tags: Ecology, Evolution, Gene drive mechanismsKoide, YS, Y.; Ikenaga, M.; Sawamura, N.; Matsubara, K.; Onishi, K.; Kanazawa, A.; Sano, Y., Heredity, 108:242-247. 2012.
Transmission ratio distortion (TRD), in which one allele is transmitted more frequently than the opposite allele, is presumed to act as a driving force in the emergence of a reproductive barrier. TRD acting in a sex-specific manner has been frequently observed in interspecific ...
B chromosomes in plants
Tags: Chromosomal drive, EvolutionJones, N, Plant Biosystems, 146:727-737. 2012.
B chromosomes (Bs) can be described as "selfish chromosomes", a term that has been used for the repetitive DNA which comprises the bulk of the genome in large genome species, except that Bs have a life of their own as independent chromosomes. They can accumulate in number by ...
Molecular dissection of Neurospora Spore killer meiotic drive elements
Tags: Gene drive mechanisms, Transmission distortionHammond, TMR, D. G.; Xiao, H.; Shiu, P. K. T., Proceedings of the National Academy of Sciences of the United States of America, 109:12093-12098. 2012.
Meiotic drive is a non-Mendelian inheritance phenomenon in which certain selfish genetic elements skew sexual transmission in their own favor. In some cases, progeny or gametes carrying a meiotic drive element can survive preferentially because it causes the death or ...
Local selection underlies the geographic distribution of sex-ratio drive in Drosophila neotestacea
Tags: Ecology, Evolution, Gene drive mechanisms, Other arthropods, X chromosomeDyer, KA, Evolution, 66:973-984. 2012.
Selfish genetic elements promote their own transmission to the next generation, often at a cost to the host individual. A sex-ratio (SR) driving X chromosome prevents the maturation of Y-bearing sperm, and as a result is transmitted to 100% of the offspring, all of which are ...
Scrambling eggs: Meiotic drive and the evolution of female recombination rates
Tags: Other arthropods, X chromosomeBrandvain, YC, G., Genetics, 190:709-723. 2012.
Theories to explain the prevalence of sex and recombination have long been a central theme of evolutionary biology. Yet despite decades of attention dedicated to the evolution of sex and recombination, the widespread pattern of sex differences in the recombination rate is not ...
Nondisjunction in favor of a Chromosome: The mechanism of rye B chromosome drive during pollen mitosis
Tags: Chromosomal drive, Gene drive mechanismsBanaei-Moghaddam, AMS, V.; Kumke, K.; Weiss, O.; Klemme, S.; Nagaki, K.; Macas, J.; Gonzalez-Sanchez, M.; Heredia, V.; Gomez-Revilla, D.; Gonzalez-Garcia, M.; Vega, J. M.; Puertas, M. J.; Houben, A., Plant Cell, 24:4124-4134. 2012.
B chromosomes (Bs) are supernumerary components of the genome and do not confer any advantages on the organisms that harbor them. The maintenance of Bs in natural populations is possible by their transmission at higher than Mendelian frequencies. Although drive is the key for ...
Evaluating the potential of the sterile insect technique for malaria control: relative fitness and mating compatibility between laboratory colonized and a wild population of Anopheles arabiensis from the Kruger National Park, South Africa
Tags: Africa, Anopheles, Sterile insect technique (SIT)G. Munhenga, B. D. Brooke, T. F. Chirwa, R. H. Hunt, M. Coetzee, D. Govender and L. L. Koekemoer, Parasites and Vectors, 4:208. 2011.
The successful suppression of a target insect population using the sterile insect technique (SIT) partly depends on the premise that the laboratory insects used for mass rearing are genetically compatible with the target population, that the mating competitiveness of laboratory ...
Field performance of engineered male mosquitoes
Tags: Gene drive synthetic, Oxitec, Sterile insect technique (SIT)A. F. Harris, D. Nimmo, A. R. McKemey, N. Kelly, S. Scaife, C. A. Donnelly, C. Beech, W. D. Petrie and L. Alphey, Nature Biotechnology, 29:1034-1037. 2011.
Mass-release of sterile male mosquitoes is a promising option for controlling dengue and malaria, but it has never been shown that lab-raised transgenic males can compete effectively with their wild counterparts outside laboratory conditions. Promising results from a restricted ...
An integrated campaign against riverine tsetse, Glossina palpalis gambiensis and Glossina tachinoides by trapping, and the release of sterile males
An integrated campaign against riverine tsetse, Glossina palpalis gambiensis and Glossina tachinoides by trapping, and the release of sterile males, International Journal of Tropical Insect Science, 5:439-442. 2011.The combination of a trapping system of insecticide impregnated screens and biconical traps followed by the release of sterile males led to the complete control of Glossina palpalis gambiensis and Glossina tachinoides in the agro-pastoral zone of Sideradougou. This area, situated ...
