Safety Assessment of Novel Genetic Technologies for Vector Control: National and International Perspectives

Novel genetic technologies provide an alternative approach for control of vectors particularly those carrying deadly pathogens. Genetic control technologies aim to either suppress target populations or modify the vector by introducing a heritable factor that reduces or blocks their ability to transmit the diseases. These technologies are thus referred to as population suppression or population modification approaches. Both these approaches offer significant advantages for vector control; however, there are associated biosafety concerns related to possible ecosystem interactions. Therefore, extensive testing on a case-by-case basis is required before these can be used as a public health intervention. This paper provides details of the international initiatives towards development of guidelines and status of regulations in India.

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