Keywords: genetically modified mosquitoes

Acceptability of emergent Aedes aegypti vector control methods in Ponce, Puerto Rico: A qualitative assessment

Pérez-Guerra CL, Rosado-Santiago C, Ramos SA, Marrero-Santos KM, González-Zeno G, Partridge SK, et al.,  PLoS Global Public Health,  2024.
Aedes aegypti control has been fraught with challenges in Puerto Rico. The government has implemented commonly used vector control methods, but arboviral epidemics still occur. It is necessary to explore new Ae. aegypti control methods. This study aimed to understand the ...
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Brazil city deploys modified mosquitos to fight dengue surge

Reuters,  The Globe and Mail,  2024.
A British biotechnology company is betting on a solution to Brazil's surging dengue cases, involving the release of genetically modified mosquitoes to reduce the viral infection's spread.
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Flight Against Infections: The Role of Genetically Engineered Mosquitoes, with Dr. Stephanie James

EeKs on Health,  YouTube,  2024.
In this episode of Causes or Cures, Dr. Eeks chats with Dr. Stephanie James about the potential use of genetically modified mosquitoes (GMMs) to fight diseases that mosquitoes carry and spread, such as Malaria and Dengue Fever. In the podcast, Dr. James provides an overview ...
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Modified mosquitoes may save millions more lives in Latin America

Marina E. Franco,  Axios,  2024.
A program that uses genetically engineered mosquitoes in Brazil, Colombia and Mexico to reduce the prevalence of diseases that can be fatal may soon serve millions more people. Why it matters: Outbreaks of dengue, chikungunya, zika and yellow fever —diseases carried by ...
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Biotech Mosquitoes Can Help to Regain Ground in Fight Against Malaria

Florence Banoba,  East News,  2024.
In response to the recent opinion articles that ran in the National print and online media in the last couple of days (1st and 5th February, 2024), regarding the use of GMO technology as a tool in the fight against malaria, I wish to address the writer’s broad-brush dismissal ...
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The fight against malaria

The Week US,  The Week,  2023.
Some scientists are betting on genetically modified mosquitoes. On the island nation of São Tomé and Príncipe, 200 miles off Africa’s west coast, University of California researchers are aiming to replace local mosquitoes with lab-tweaked insects that can’t transmit the ...
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How Genetically Modified Mosquitos can end malaria in Africa – Dr. Santos

S. Akioye,  The Star,  2023.
With over 200 million cases every year and nearly 700,000 deaths, Malaria is currently one of Africa’s most dreaded sicknesses. While there have been efforts at finding different drugs for treatment, scientists are working on an innovative solution using genetically modified ...
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Unleashing a New Weapon on the Mosquito: A Mosquito

S. Nolen and E. Lutz,  New York Times,  2023.
Five decades ago, entomologists confronting the many kinds of suffering that mosquitoes inflict on humans began to consider a new idea: What if, instead of killing the mosquitoes (a losing proposition in most places), you could disarm them? Even if you couldn’t keep them from ...
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The Gamble: Can Genetically Modified Mosquitoes End Disease?

S. Nolen,  New York Times,  2023.
The malaria situation in São Tomé and Príncipe, an African island nation with a population of 200,000, epitomizes the current challenge in the global struggle against the disease. The country is among the world’s least developed, and it has depended on foreign aid to fight ...
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Could a new gene-editing technique be a major breakthrough in the battle against malaria?

B. Cottam,  GEOGRAPHICAL,  2023.
The idea is that since female mosquitoes typically only mate once, the mass release of the sterile male mosquitoes should prevent wild females from producing future generations. Insect populations can and have already been successfully suppressed by the release of sterilised ...
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Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes

I. Sanchez-Vargas, A. E. Williams, L. E. Martin, I. Martin-Martin, S. Bennett, K. E. Olson and E. Calvo,  Journal of Visualized Experiments,  2023.
Transgenic mosquitoes often display fitness costs compared to their wild-type counterparts. In this regard, fitness cost studies involve collecting life parameter data from genetically modified mosquitoes and comparing them to mosquitoes lacking transgenes from the same genetic ...
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High-efficiency gene editing in Anopheles sinensis using ReMOT control

X.-l. Yang, X. Ling, Q. Sun, P.-p. Qiu, K. Xiang, u.-f. JHong, S.-l. He, J. Chen, X. Ding, H. Hu, Z.-b. He, C. Zhou, B. Chen and L. Qiao,  bioRxiv,  2023.08.29.555096. 2023.
CRISPR/Cas9-mediated gene editing provides an effective method for deciphering the molecular mechanisms underlying mosquito development and mosquito-borne disease transmission, as well as for exploring genetic control strategies. However, delivering the Cas9 ribonucleoprotein ...
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How genetically modifying mosquitoes could strengthen the world’s war on malaria

S. Oliver and J. Raman,  The Conversation,  2023.
Mosquitoes can be genetically modified through two different technologies. The first method, paratransgenesis, involves infecting mosquitoes with bacteria that prevent them from transmitting malaria. This doesn’t harm the mosquito. It is important not to eliminate or harm ...
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Baker: New tools can change mosquitoes’ DNA, but should it be done?

K. Baker,  Fremont News Messenger,  2023.
Suppose Sauron — or perhaps Gandalf — were to offer you a magical golden ring with the power to rid the world of mosquitoes once and for all. And with their demise, to save countless human lives from the many diseases for which mosquitoes are the sole or primary vectors: ...
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Cost-effectiveness of Precision Guided SIT for Control of Anopheles gambiae in the Upper River Region, The Gambia

G. William, R. Robyn, M. Agastya, M. S. C. Hector, S. Andrea, Z. David, G. I. Patrick, D. Umberto, Alessandro, M. M. John and A. Omar,  bioRxiv,  2023.07.20.549762. 2023.
Precision-guided sterile insect technique (pgSIT) is an extremely promising vector control intervention that can reduce and potentially eliminate the unacceptable malaria burden, particularly in sub-Saharan Africa. Here we explore the cost effectiveness of using this approach in ...
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Eliminating Malaria Vectors with Precision Guided Sterile Males

L. S. Andrea, A. A. Reema, J. P. James, L. C. Martha, C. Sanle, M. Agastya, M. S. C. Hector, A. Igor, M. M. John and S. A. Omar,  bioRxiv,  2023.07.20.549947. 2023.
Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is considered essential to curtail malaria transmission. However existing vector control technologies rely on insecticides, which are becoming increasingly ineffective. Sterile insect technique ...
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Unleashing the swarm: Battling the global mosquito menace and defending public health

J. Entine and S. Moxon,  Genetic Literacy Project,  2023.
There is one solution embraced by global health experts that should be pursued aggressively, if with some caution. Scientists in real-world trials have altered the genomes of entire animal populations, including mosquitoes, to thwart the vectoring of diseases and control pests ...
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Malaria Cases In U.S. Trigger Unfounded Claims About Bill Gates, Mosquito Project

B. Y. Lee,  Forbes,  2023.
When the U.S. Centers for Disease Control and Prevention (CDC) issued an alert about finding four malaria cases in Florida and one malaria case in Texas, it created quite a buzz. After all, these were the first reported cases of people actually catching malaria in the U.S. since ...
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How genetically modified mosquitoes could eradicate malaria

S. Jones,  Nature,  2023.
Malaria is caused by Plasmodium parasites that are transmitted from person to person by Anopheles mosquitoes — often Anopheles gambiae, the primary vector in sub-Saharan Africa. Many approaches to malaria control focus on mosquitoes. Insecticide-treated mosquito nets and indoor ...
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Combining two genetic sexing strains allows sorting of non-transgenic males for Aedes genetic control

C. Lutrat, M. Burckbuchler, R. P. Olmo, R. Beugnon, A. Fontaine, O. S. Akbari, R. Argilés-Herrero, T. Baldet, J. Bouyer and E. Marois,  Communications Biology,  6:646. 2023.
Chemical control of disease vectoring mosquitoes Aedes albopictus and Aedes aegypti is costly, unsustainable, and increasingly ineffective due to the spread of insecticide resistance. The Sterile Insect Technique is a valuable alternative but is limited by slow, error-prone, and ...
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Requirements for market entry of gene drive-modified mosquitoes for control of vector-borne diseases: analogies to other biologic and biotechnology products

S. L. James, H. Quemada, M. Q. Benedict and B. Dass,  Frontiers in Bioengineering and Biotechnology,  11:1205865. 2023.
Gene drive-modified mosquitoes (GDMMs) are proposed as new tools for control and elimination of malaria and other mosquito-borne diseases, and promising results have been observed from testing conducted in containment. Although still at an early stage of development, it is ...
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Genetically Engineered Mosquito experiment in California’s Central Valley halted

H. Bourque,  Friends of the Earth,  2023.
In a victory for environmentalists, scientists and vulnerable agricultural communities across California, the California Department of Pesticide Regulation (DPR) announced yesterday the withdrawal of a permit request for a mass release of experimental genetically engineered ...
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updated: Genetically Engineered Mosquitoes Research Authorization Application

California Department of Pesticide Regulation,  California Department of Pesticide Regulation,,  2023.
In May 2023, Oxitec voluntarily withdrew its research authorization application to test the use of genetically engineered mosquitoes in California. DPR did not issue a decision on the application. For more information on Oxitec’s withdrawal and future plans for research in ...
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DIPA-CRISPR gene editing in the yellow fever mosquito <em>Aedes aegypti</em> (Diptera: Culicidae)

S. Yu, T. Momoyo, O. Manabu, K. Hirotaka and D. Takaaki,  bioRxiv,  2023.04.07.535996. 2023.
Current methods for gene editing in insects rely on embryonic microinjection, which can be challenging for non-specialist laboratories. Recently, an alternative method known as direct parental CRISPR (DIPA-CRISPR) was developed. This method involves injecting commercial Cas9 ...
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Health experts meet in Dar over use of GMO mosquitoes to fight Malaria

M. Chelangat,  NATION,  2022.
Regional health think thanks led by the African Institute for Development and Policy (AFIDEP), East African Community(EAC) Health department, East African Health Research Commission and Ifakara health institute will be meeting in Dar es Salaam, Tanzania for three day starting ...
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Calif. Legislature bites back at GE mosquito releases

L. Patrick,  Sun Gazette,  2022.
A biotech company created millions of genetically modified mosquitoes, but not in the Jurassic Park sense. The lab grown species could actually lower the population of an invasive mosquito that carries a plethora of diseases on its shoulders.On Nov. 3, several members of the ...
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Genetically modified mosquitoes cut the insect’s number by 96 per cent

M. Fauzia,  NewScientist,  2022.
The release of genetically modified male mosquitoes into a city in Brazil temporarily cut the virus-carrying insects by up to 96 per cent. Although not a permanent fix, periodically releasing such mosquitoes could reduce the burden of infections including dengue, malaria and ...
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Combining transgenesis with paratransgenesis to fight malaria

W. Huang, J. Vega-Rodriguez, C. Kizito, S.-J. Cha and M. Jacobs-Lorena,  eLife,  11:e77584. 2022.
Malaria is among the deadliest infectious diseases, and Plasmodium, the causative agent, needs to complete a complex development cycle in its vector mosquito for transmission to occur. Two promising strategies to curb transmission are transgenesis, consisting of genetically ...
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Explained: How scientists engineered mosquitoes that cannot spread malaria

FP Explainers,  Firstpost,  2022.
The world of science is reaching new heights. Scientists have now developed mosquitoes that will bite you but not cause malaria. The study was conducted by a team of researchers called Transmission: Zero at the Imperial College of London. The results of the research were ...
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Points to consider in seeking biosafety approval for research, testing, and environmental release of experimental genetically modified biocontrol products during research and development

W. K. Tonui, V. Ahuja, C. J. Beech, J. B. Connolly, B. Dass, D. C. M. Glandorf, et al.,  Transgenic Research,  2022.
Novel genetically modified biological control products (referred to as “GM biocontrol products”) are being considered to address a range of complex problems in public health, conservation, and agriculture, including preventing the transmission of vector-borne parasitic and ...
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Malaria Gene Drives: A Battle Of Wit Between The Government And Stakeholders

O. Onwumere,  The Nigerian Voice,  2022.
Through the National Biosafety Management Agency (NBMA), guidelines for gene editing, primarily in agriculture, were approved by the Nigerian Federal Government in December 2020. As the first country in Africa, the government was praised for taking the momentous step of ...
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Gene drive used to make all female mosquitoes sterile

Akfire1,  TechiLink,  2022.
We have long known that we can limit malaria infections by controlling the mosquitoes that transmit them. But that knowledge has not translated into auditing efforts that have always been completely successful. Many of the approaches we have used to control mosquitoes have caused ...
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How We’re Reducing Disease With Genetically Modified Mosquitoes

V. Wise,  HealthMatch,  2022.
We all know mosquitoes as those annoying insects we swat away from our faces. They carry diseases, so we don’t want them anywhere near us. There are over 200 types of wild mosquitoes bugging us across America and the U.S. territories. Approximately 12 types can spread disease, ...
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Humans Have a Long History of Making ‘Very Bad Decisions’ to Save Animals

T. McDonnell,  The New York Times,  2022.
Environmental reporter Tim McDonnell on the potential negative consequences of animal conservation efforts. McDonnell highlights Target Malaria’s research on gene drive to “eliminate malaria-carrying mosquitos” and quotes New Zealand researcher Philipp Messer saying that ...
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Fact Check: Bill Gates’ genetically modified mosquitoes are responsible for mosquito-borne viruses in Florida and are part of the next planned pandemic.

A. Williams,  The Paradise,  2022.
The genetically modified mosquitoes in Florida are part of a project by Oxitec that Bill Gates did not fund. The virus reported in Florida is the West Nile virus, which has had reported cases in most U.S. states since 1999, with lower cases in 2022 than in previous years. The ...
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Can mosquitoes be used for biological warfare?

Health Desk,  Health Desk,  2022.
Every year, mosquitoes kill more people than any other creature in the world. Because of 1) mosquitoes’ ability to spread deadly, communicable diseases and cover large distances quickly, and 2) the fact that different types of bugs have been weaponized for hundreds of years, it ...
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Modified mosquito releases to fight dengue fever, chikungunya or yellow fever

Sewell, Tammy,  OICANADIAN,  2022.
To date, only one technique based on genetically modified mosquitoes has been developed at an operational level, it is the RIDL technique (release of insects carrying a dominant lethal gene, or release of insects carrying a dominant lethality gene). Male mosquitoes which, unlike ...
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Life-history traits of a fluorescent Anopheles arabiensis genetic sexing strain introgressed into South African genomic background

N. L. Ntoyi, T. Mashatola, J. Bouyer, C. Kraupa, H. Maiga, W. Mamai, N. S. Bimbile-Somda, T. Wallner, D. O. Carvalho, G. Munhenga and H. Yamada,  Malaria Journal,  21:12. 2022.
Background South Africa has set a mandate to eliminate local malaria transmission by 2023. In pursuit of this objective a Sterile Insect Technique programme targeting the main vector Anopheles arabiensis is currently under development. Significant progress has been made towards ...
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Infravec2 guidelines for the design and operation of containment level 2 and 3 insectaries in Europe

E. Pondeville, A.-B. Failloux, F. Simard, P. Volf, A. Crisanti, R. E. Haghighat-Khah, N. Busquets, F. X. Abad, A. J. Wilson, R. Bellini, S. Marsh Arnaud, A. Kohl and E. Veronesi,  Pathogens and Global Health,  2022.
ABSTRACTWith the current expansion of vector-based research and an increasing number of facilities rearing arthropod vectors and infecting them with pathogens, common measures for containment of arthropods as well as manipulation of pathogens are becoming essential for the design ...
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World Mosquito Day: Can genetic modification techniques quash the menace?

CNBCTV18,  CNBC TV18,  2022.
Genetically modified (GM) mosquitoes are prepared in labs and are supposed to fight the Aedes aegypti mosquitoes which spread viruses including dengue, Zika, and chikungunya. Billions have apparently been successfully released in the US, Brazil, the Cayman Islands, Panama, and ...
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Outbreaks of arboviruses, biotechnological innovations and vector control: facing the unexpected

C. Boëte,  Innovative Strategies for Vector Control,  6:219-231. 2022.
Outbreaks of arboviruses have occurred in the last decades in many places around the world and a variety of responses have been taken in order to control them. Responses ranged from vaccination campaigns to the use of conventional vector control methods. Innovative approaches ...
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Release the Beast? Genetically modified mosquitos for diease control

G. Ferrante,  Palatinate,  2022.
The company Oxitec is an example how genetic technologies can be used in managing unwanted species in a sustainable way.Oxitec jumped to the headlines in March with permits being issued by the United States Environmental Protection Agency (EPA) to allow the release of around 2.4 ...
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Gene drives and Africa’s battle against malaria

Annonymous,  Africa Verified,  2022.
As malaria cases rise, and the effectiveness of current methods begins to fall, the WHO’s target of reducing the global malaria burden by 90% by 2030 will not be met. It is critical for new and resilient treatment, prevention, and control methods to be developed and integrated ...
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Inside the Plan to Release Life-Saving Mosquitoes

WIRED,  WIRED,  2022.
The Florida Keys Mosquito Control District is turning towards a novel tool to combat harmful insecticide-resistant mosquitoes like the Aedes aegypti. What are they doing exactly? They're releasing millions of genetically modified male mosquitoes engineered to reduce the ...
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Genetically Modified Mosquitoes to Fight Malaria in Nigeria, Burkina Faso, Mali and Uganda: What Legal Response?

O. J. L. Tung,  Potchefstroom Electronic Law Journal,  25:1-42. 2022.
Advanced applied research on genetically modified (hereafter GM) insects is being undertaken to control insect vectors of human diseases such as mosquitoes. GM insect technologies are being developed in countries where there is a legal ...
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Modifying mosquitoes to suppress disease transmission: Is the long wait over?

J. R. Powell,  Genetics,  2022.
For more than 50 years it has been a dream of medical entomologists and public health workers to control diseases like malaria and dengue fever by modifying, through genetics and other methods, the arthropods that transmit them to humans. A brief synopsis of the history of ...
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Unfolding the Next Frontier of Innovation in Malaria: The Way Forward

ETHealthWorld,  ET Healthworld,  2022.
Malaria innovation is on the verge of a challenging yet exciting frontier. Therefore, to ramp up current innovatins and expand effective therapeutic and prevenitive methods, the governments, international organizations, and the private sector must work together. Additionally, ...
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Fighting Malaria With Genetically Modified Mosquitoes

K. Ferris,  Liberty Nation News,  2022.
Nearly half of the world's population inhabits an area at risk for malaria – but scientists hope to change that. Through the engineering of gene drives, malaria-transmitting mosquitoes could be irradiated completely. That might sound like a great idea, but scientists and ...
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Mosquitoes Genetically Modified to Stop Disease Pass Early Test

L. Rapaport,  WebMD,  2022.
Genetically modified mosquitoes released in the U.S. appear to have passed an early test that suggests they might one day help reduce the population of insects that transmit infectious diseases. As part of the test, scientists released nearly 5 million genetically engineered ...
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Squashing malaria could save as many lives as covid-19 has taken

Anonymous,  The Economist,  2022.
When it comes to covid-19 vaccines, poor countries in Africa have been stuck at the back of the queue. However, the continent’s long wait for another immunological miracle appears to be drawing to a close. Later this year, the world’s first malaria vaccine is scheduled for a ...
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Sterilizing Male Mosquitoes with Gene Editing to Reduce Disease Spread

Global Biodefense Staff,  Global Biodefense,  2021.
Researchers at the Army’s Institute for Collaborative Biotechnologies and the University of California Santa Barbara used a gene editing tool known as CRISPR-Cas9 to target a specific gene tied to fertility in male mosquitoes. Researchers experimented with the Aedes aegypti ...
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Why Genes That Make Mosquitoes Glow Can Help Reduce Vector-Borne Disease

E. Ricciuti,  Entomology Today,  2021.
Fireflies they are not, but glow they do. Not in the dark, to be sure, but mosquitoes genetically modified in the laboratory for an emerging approach to reducing the threat of vector-borne disease look like miniature neon signs when subjected to ultraviolet light. To produce ...
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2021 WHO guidelines on genetically modified mosquitoes

M. Makoni,  The Lancet Microbe,  2:e353. 2021.
On May 19, 2021, WHO updated its guidelines for research and development on genetically modified mosquitoes, which define the standards for decision-making about how and when testing should proceed and describe best practices to ensure that research done in a public health ...
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The Aedes aegypti (Diptera: Culicidae) hsp83 Gene Promoter Drives Strong Ubiquitous DsRed and ZsGreen Marker Expression in Transgenic Mosquitoes

S. H. Webster and M. J. Scott,  Journal of Medical Entomology,  2021.
Transgenic strains of the mosquito disease vector Aedes aegypti (L.) are being developed for population suppression or modification. Transgenic mosquitoes are identified using fluorescent protein genes. Here we describe DsRed and ZsGreen marker genes driven by the constitutive ...
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Genetically modified mosquitoes and Africa

S. Bagcchi,  Sci Dev Net,  2021.
The World Health Organization (WHO) has released new guidance for the deployment of genetically modified (GM) mosquitoes to combat vector-borne diseases like malaria and dengue. GM mosquitoes may carry a gene that kills female progeny and the technology can be used against the ...
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Mutant mosquitoes carrying ‘death gene’ released as ‘bio-engineered’ insects terrify

J. Caven,  Daily Star,  2021.
Mutant mosquitoes which carry a ‘death gene’ have been released into the skies in a bid to curb diseases from spreading to humans. Tens of thousands of genetically modified male insects will mate with female Aedes aegypti mosquitoes, which transmit illnesses, in Florida ...
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‘Death gene’ in genetically modified male mosquitoes

J. Goddard,  The Times,  2021.
Tens of thousands of bio-engineered mosquitoes have taken flight in the Florida Keys under a pilot project that aims to breed insects programmed with a “death switch”. Genetically modified males produced by Oxitec — a British-founded biotechnology company — have begun ...
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New CRISPR Tools Can Help Contain Mosquito Disease Transmission

Anonymous,  labcompare,  2021.
Scientists have now developed several genetic editing tools that help pave the way to an eventual gene drive designed to stop Culex mosquitoes from spreading disease. As detailed in the journal Nature Communications, Xuechun Feng, Valentino Gantz and their colleagues at Harvard ...
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African Experts Welcome WHO Guidance on Ethics, Standards, and Governance of Genetically Modified Mosquito Research

E. Nakkazi,  Health Policy Watch,  2021.
Researchers engaged in mosquito gene drive technologies are optimistic that new World Health Organization (WHO) guidance on best research practices will ensure that their work is safe and ethical. Such guidance also helps research results advance from laboratories to be used in ...
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WHO releases new guidance for deployment of genetically modified mosquitoes

E. Henderson,  News Medical Life Sciences,  2021.
The World Health Organization (WHO) has released new guidance for the deployment of genetically modified (GM) mosquitoes to combat vector-borne diseases like malaria and dengue. GM mosquitoes may carry a gene that kills female progeny and the technology can be used against the ...
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Researchers Create New CRISPR Tools to Help Contain Mosquito Disease Transmission

M. Aguilera,  UC San Diego News Center,  2021.
Much less genetic engineering has been devoted to Culex genus mosquitoes, which spread devastating afflictions stemming from West Nile virus—the leading cause of mosquito-borne disease in the continental United States—as well as other viruses such as the Japanese encephalitis ...
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New CRISPR tools help contain mosquito disease transmission: Genetics toolkit targets less researched Culex mosquitoes, which transmit West Nile virus and avian malaria.

University of California - San Diego,  ScienceDaily,  2021.
Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and Aedes species, which spread malaria, dengue and other ...
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Mosquitoes are deadly pests, genetically-modified mosquitoes could help stop disease

T. Browne,  ClickOrlando,  2021.
Hearing the words “genetically modified mosquitoes” can sound like the plot for a science-fiction movie but Meredith Fenson, a native Floridian turned biological pest control specialist says, “mosquitoes are the world’s deadliest animal by far” and a study happening ...
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Genetically Modified Mosquitoes: What to Know

N. Pathak,  WebMD,  2021.
It sounds like something out of a movie: a biotech company releases genetically modified mosquitoes into the wild. But this is the real deal, a test that’s been done in a handful of countries around the world and that is underway in the U.S. Scientists hope these bugs can help ...
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Q&A: WHO updates guidance on testing genetically modified mosquitoes

E. N. Dreisbach,  Healio,  2021.
Researchers have been exploring the use of genetically modified mosquitos as a potential control method for vector-borne diseases. Just last month, Oxitec began releasing its genetically modified (GM), self-limiting male Aedes aegypti mosquitoes in the Florida Keys in the hope of ...
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Genetically modified mosquitoes; WHO issues new guidance for research

DTE Staff,  Down To Earth,  2021.
Genetically-modified mosquitoes or GMMs have been used across the world to control mosquitoes. GMMs have been able to bring down the population of the Aedes aegypti by 90 per cent in countries like Brazil, the Cayman Islands, Panama and Malaysia. But there have never been any ...
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Burkina Faso Testing Genetically Modified Mosquitoes to Curb Malaria

H. Wilkins,  Voice of America,  2021.
The mosquito-borne disease malaria kills more than 400,000 people each year, the vast majority in Africa. Target Malaria, an international group of scientists, is working in Burkina Faso on a genetic solution. Abdoulaye Diabate, with the West African country’s Research ...
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Florida Environmental Group Says GMO Mosquitoes Fall Short on Scientific Rigor

C. Drukier,  NTD,  2021.
America’s first genetically modified mosquitoes are now buzzing around six locations in the Florida Keys as part of a pilot project. Developed by UK biotech company Oxitec, the bugs are designed to kill off the wild population of Aedes aegypti mosquitoes that carry diseases ...
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Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes

X. Feng, V. López Del Amo, E. Mameli, M. Lee, A. L. Bishop, N. Perrimon and V. M. Gantz,  Nature Communications,  12:2960. 2021.
Culex mosquitoes are a global vector for multiple human and animal diseases, including West Nile virus, lymphatic filariasis, and avian malaria, posing a constant threat to public health, livestock, companion animals, and endangered birds. While rising insecticide resistance has ...
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WHO issues new guidance for research on genetically modified mosquitoes to fight malaria and other vector-borne diseases

WHO,  reliefweb,  2021.
New guidance from the World Health Organization (WHO) sets essential standards to inform future research and development on genetically modified mosquitoes, particularly in addressing issues relating to ethics, safety, affordability and effectiveness. Malaria and other ...
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Guidance framework for testing of genetically modified mosquitoes, second edition

WHO,  WHO-TDR,  2021.
For more than 2 decades, scientists have been working to harness the promise of molecular biology to develop genetically modified mosquitoes (GMMs) for use as public health tools to prevent the transmission of vector-borne diseases. Responding to a need for additional standards ...
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Genetically Modified Mosquitoes Take Flight to Fight Invasive Species in Florid

T. Machemer,  Smithosonian Magazine,  2021.
In late April, the biotechnology company Oxitec placed blue-and-white hexagonal boxes on the properties of six private volunteers around the Florida Keys. After pouring in water, the genetically modified mosquito eggs inside activated and hatched. Now the first larvae have ...
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Genetically modified mosquitoes may help scientists swat dreaded midge

W. Jean,  The Times,  2021.
Scotland’s bloodthirsty midges may finally meet their match thanks to revolutionary genetic manipulation techniques that could stop the pesky insects biting chunks out of the tourist industry. News that a British biotechnology company has created genetically modified non-biting ...
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First Genetically Modified Mosquitoes Released in U.S. Are Hatching Now

D. Coffey,  Scientific American,  2021.
This week, mosquito eggs placed in the Florida Keys are expected to hatch tens of thousands of genetically modified mosquitoes, a result of the first U.S. release of such insects in the wild. A biotechnology firm called Oxitec delivered the eggs in late April as part of a ...
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In a World-First, Genetically Modified Mosquitoes Are Hatching in the US

B. Bergan,  INTERSTING ENGINEERING,  2021.
Mosquito eggs placed in the Florida Keys are about to hatch tens of thousands of genetically altered mosquitos, the first such release of "synthetic" insects in the world, according to an initial report from Scientific American. Pilot program for genetically modified mosquitoes ...
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The U.S.’s first open-air genetically modified mosquitoes have taken flight

S. Milius,  Science News,  2021.
The first genetically modified mosquitoes that will be allowed to fly free outdoors in the United States have started reaching the age for mating in the Florida Keys. In a test of the biotech company Oxitec’s GM male mosquitoes for pest control, these Aedes aegypti started ...
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Use of genetically modifed mosquitoes to minimize the burden of diseases casused by mosquitoes in South Texas.

MDN Staff,  MegaDoctor News,  2021.
Of the many species of mosquitoes, female Aedes aegypti is the primary vector that is responsible for transmission of several diseases and has been most extensively studied. The efforts of the World Health Organization and the Center for Disease Control and Prevention to prevent ...
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Monster Mosquito–Why the Technology of Genetically Modified Mosquitoes is Dangerous and Should Be Stopped Worldwide

B. Dogra,  counter currents,  2021.
After sparking controversy in other countries including India, the technology of genetically engineered mosquitoes is now leading to widespread protests in Florida USA. Here the biotechnology giant company Oxitec in collaboration with local officialdom is moving ahead with a ...
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Florida releases genetically modified mosquitoes in hopes to reduce spread of disease

A. Fahim,  Reuters,  2021.
Genetically modified mosquitoes have been released for the first time in the United States, taking flight in the Florida Keys in a pilot program intended to reduce the spread of deadly diseases such as dengue, yellow fever and the Zika virus.After an odyssey spanning more than a ...
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Why Florida is releasing genetically modified mosquitoes

M. Murphy,  The Telegraph,  2021.
The thousands of lab-grown mosquitoes hatching in humid gardens across Florida’s tropical Key West next week will be blissfully ignorant of the controversy they have caused. Billboards have already begun appearing near busy motorways in protest of their arrival, with one ...
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Genetically Modified Mosquitoes Have Come to the U.S. Will They Work?

A. de la Garza,  TIME,  2021.
“Our Mosquito Project Takes Flight,” reads a baby-blue billboard off US-1 in the Florida Keys, alongside an image of an insect tracing a path in the shape of a heart. Sponsored by the local mosquito control board and U.K.-based biotech firm Oxitec, the ad promotes a ...
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Bill Gates finances the creation of transgenic mosquitoes

Explica.co,  explica,  2021.
Male mosquitoes (they do not bite. They feed on nectar, not blood) from Oxitec will emerge from release boxes placed in six locations in the Florida Keys to mate with local female mosquitoes (they do bite. They do feed on blood). The female offspring from these encounters cannot ...
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Genetically Modified Mosquitoes Released In US For First Time To Combat Disease

J. Van Zijl,  IFL Science,  2021.
A landmark project, spearheaded by the biotechnology company, Oxitec, has released genetically modified mosquitos in the Florida Keys. This marks the first time that genetically modified mosquitos have been released into the wild in the US. The reason: to combat the Aedes aegypti ...
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Genetically Modified Mosquitoes Released In Florida ‘Jurassic Park Experiment’

D. Richardson,  UNILAD,  2021.
Mosquitos are not only annoying but they can carry disease in their bites. In response to this, a company called Oxitec has genetically modified male mosquitos to pass on a killswitch to females. It is hoped that these genetically modified pests will help stop the transmission of ...
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Gravitas: Genetically modified mosquitoes arrive in Florida

P. Sharma,  WION,  2021.
Genetically engineered mosquitoes have arrived in U.S. 20 million 'modified mosquitoes' will be released in Florida to help prevent Dengue. But, Florida residents fear a 'mosquito apocalypse'
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Reengineered mosquitoes released in Florida pilot program

S. W. Tan,  The Washington Times,  2021.
Genetically engineered mosquitoes have been released in the U.S. for the first time in the Florida Keys, with hopes of quelling wild, disease-carrying mosquito populations in the region. British-based biotech firm Oxitec genetically engineered Aedes aegypti non-biting male ...
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First genetically modified mosquitoes released in US

N. Lanese,  LiveScience,  2021.
The biotech firm Oxitec has released its genetically modified mosquitoes in the Florida Keys, with the goal of suppressing wild, disease-carrying mosquito populations in the region. This is the first time genetically modified mosquitoes have been released in the U.S. Oxitec ...
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Bill Gates-backed startup releases millions of genetically modified mosquitoes

ENTREPRENEUR STAFF,  Entrepreneur,  2021.
The British company Oxitec released a cloud of hundreds of millions of genetically modified mosquitoes to study how to control their reproduction and thus stop the spread of dengue, Zika, malaria, etc. As reported by Axios , the company, which is funded by the Bill and Melinda ...
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First US Field Test of GM Mosquitoes Begins in Florida

C. Wilcox,  The Scientist,  2021.
he first US field test of genetically modified mosquitoes for population control has begun in Florida. Approximately 144,000 mosquitoes engineered by the UK-based biotech firm Oxitec are to be expected to be set free over the next three months, the first of up to 750 million ...
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The first transgenic mosquitoes were releaseed in the United States.

D. Davis,  Prudent Press Agency,  2021.
After a decade of fighting for regulatory approval and public acceptance, the biotech company has released GMO mosquitoes outdoors in the United States for the first time. The experiment, which began this week in the Florida Keys, despite objections from some local critics, is ...
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The Bill Gates Corporation, Backed by Bill Gates, Releases Thousands of Genetically Modified Mosquitoes

T. Meeks,  Aviation Analysis,  2021.
British company Oxitec has launched transgenic mosquitoes in the Florida Keys, in the United States, to study how to control their reproduction and thus limit the spread of chronic diseases transmitted by insects such as dengue fever and the Zika virus. The company, funded by ...
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Genetically modified mosquitos: Biohacking for disease prevention.

D. Maloney,  HACKADAY,  2021.
Mosquito control is basically a numbers game, stacked in their favor. Since each female lays 100 to 200 eggs in a clutch, in wet climates, mosquitos are simply too prolific to get ahead of using standard means. Coupled with collateral damage to the environment — draining ...
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First genetically modified mosquitoes released in the United States

E. Waltz,  Nature,  2021.
After a decade of fighting for regulatory approval and public acceptance, a biotechnology firm has released genetically engineered mosquitoes into the open air in the United States for the first time. The experiment, launched this week in the Florida Keys — over the objections ...
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Oxitec releases first genetically modified mosquitoes in U.S.

J. Knutson,  Axios,  2021.
Oxitec, a British startup determined to prevent instances of mosquito-borne disease, released thousands of genetically modified mosquito eggs in the Florida Keys this week as part of a test approved by the Environmental Protection Agency and Florida's agriculture department. Why ...
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Genetically modified mosquitoes have landed in the Keys. Here’s what you need to know

G. Filosa,  Miami Herald,  2021.
More than 20 million genetically modified mosquitoes are coming to the Florida Keys this year, in a landmark project by British biotech company Oxitec and Monroe County’s Mosquito Control District. This mosquito control method hasn’t been used in the U.S. before. It’s a ...
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What Are GMO Mosquitoes and What Is Their Purpose?

A. Krosofsky,  GREENMATTERS,  2021.
Scientists have made GMO corn, strawberries, even many types of farm animals. Now, it seems, they have managed to genetically modify mosquitoes as well. But what is the purpose of GMO mosquitoes, and why would scientists go out of their way to create something that is already a ...
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Genetically modified mosquitoes | Connect the Dots

thv11,  THV11,  2021.
This is a local TV story from Arkansas of the Oxitec trial being conducted in Florida.
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‘Home to GMO Mosquitoes?!’ Florida Unleashes a Billion Lab Grown Mosquitoes

Anonymous,  B and T MAGAZINE,  2021.
Up to a billion genetically engineered mosquitoes are going to be released in the Florida Keys—but locals are having none of it, with billboards erected saying ‘no!’ to the damned blood suckers. The genetically-modified mosquitoes, known as the OX5034, were made in a ...
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The Release of 1 Billion Exterminator Mosquitoes Has Begun

D. Noor,  Gizmodo,  2021.
Tens of thousands of male mosquitoes are descending on the Florida Keys. But these are no ordinary mosquitoes: They’re genetically modified, and they were planted around the state on purpose. It’s part of a plan to curb disease by releasing 1 billion mosquitoes across two ...
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First-ever US release of genetically modified mosquitoes begins in Florida Keys

S. LaMotte,  CNN,  2021.
The first release of genetically modified mosquitoes in the United States began this week in the Florida Keys -- the culmination of a decade-long effort by local mosquito control authorities to see if a genetically modified organism is a viable alternative to spraying ...
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Driving genetic destruction

Anonymous,  Alliance for Natural Health,  2021.
Genetically-engineered (GE) mosquitoes have been released in a number of countries, including the US. We’ve known for some time that these experiments have not gone to plan, but a new paper provides a better understanding of how they’ve went awry, and provides a harrowing ...
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The first genetically modified mosquitoes released in the U.S. to buzz in the Florida Keys

K. Weintraub,  USA Today,  2021.
On Thursday morning, workers from a British company placed basketball-sized cardboard boxes into six yards in the Florida Keys. Then they added water. In a week or so, 12,000 male Aedes aegypti mosquitoes will – one by one – begin buzzing out of each box, the first ...
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A Billion Lab-Grown Mosquitos Are Being Released and People Are Freaking Out

V. Kipnis,  Vice,  2021.
On Thursday afternoon, six Florida Keys residents will walk out into their yards and set out aquamarine cardboard boxes filled with mosquito larvae. Then, water will be poured into the containers. For the next ten days, as the mosquitoes grow into adults, their neighbors will be ...
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The mosquito-bite fight begins

F. Billingsley,  Click2Houston,  2021.
Anyone who thought February’s freeze would kill all the mosquitos is biting up the wrong leg. They are back and, seemingly so, with a vengeance (did surviving just make them stronger, one wonders?). In Florida this week, an interesting and controversial fight against the bite ...
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Nearly 144K GMO Mosquitoes to be Released in South Florida: What We Know

J. Prigeon,  6 South Florida,  2021.
Nearly 144,000 genetically modified mosquitoes will be released in South Florida this week as part of an effort to reduce the population disease-carrying mosquitoes. The landmark release of GMO insects marks the beginning of the U.S.-approved program to control the number of ...
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Selection of Sites for Field Trials of Genetically Engineered Mosquitoes with Gene Drive

G. C. Lanzaro, M. Campos, M. Crepeau, A. Cornel, A. Estrada, H. Gripkey, Z. Haddad, A. Kormos, S. Palomares and W. Sharpee,  bioRxiv,  2021.04.28.441877. 2021.
Novel malaria control strategies using genetically engineered mosquitoes (GEMs) are on the horizon. Population modification is one approach wherein mosquitoes are engineered with genes rendering them refractory to the malaria parasite coupled with a low-threshold, Cas9-based gene ...
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Nation’s first trial of genetically modified mosquitoes starts in Florida Keys

S. Brock,  TODAY,  2021.
To control the population of potentially disease-spreading mosquitoes, a controversial project is getting underway in the Florida Keys, highlighted by the release of even more mosquitoes that have been genetically modified. NBC’s Sam Brock reports for TODAY from Miami.
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Florida Unleashing Thousands of Mosquitoes

Anonymous,  The Weather Channel,  2021.
Florida will begin releasing thousands of genetically modified mosquitoes in the Keys this week to combat diseases like Zika and dengue. But the government’s green light has some residents seeing red.
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GMO mosquitoes to be released in Florida Keys

NBC News,  WRCBtv,  2021.
Florida will begin releasing genetically modified mosquitoes this week as part of its efforts to control one of the disease-spreading species of the biting insect. The state will release almost 144,000 nonbiting male mosquitoes in the coming weeks engineered by the British firm ...
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Nearly 150,000 Gene-Hacked Mosquitoes to Be Unleashed in Florida

S. Kim,  Newsweek,  2021.
Nearly 150,000 mosquitoes that have been genetically modified by Oxitec, a biotechnology company based in the U.K., will be released across parts of Monroe County's Florida Keys region starting this week. The release is part of an experiment to help combat a disease-transmitting ...
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Genetically modified mosquito larvae to be released in Florida Keys

E. Helmore,  The Guardian,  2021.
The Florida Keys will this week see the release of genetically modified, non-biting male mosquito larvae as part of a controversial program designed to curb the spread of insect-borne diseases such as dengue, Zika and yellow fever. The Florida Keys Mosquito Control District and ...
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Florida set to release swarms of GMO mosquitoes as residents decry ‘criminal experiment’ by Bill Gates-backed biotech

rt com,  rt com,  2021.
A plan to release thousands of genetically modified mosquitoes in an effort to combat disease in the Florida Keys has triggered dire concerns among locals, some saying the “criminal” experiment will turn them into guinea pigs. Spearheaded by the Florida Keys Mosquito Control ...
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BUZZ OFF Florida residents blast pest control ‘TERRORISTS’ over plans to unleash a BILLION mutant mosquitoes in the Keys

J. Bentley-York,  The SUN,  2021.
The areas Mosquito Control District (FKMCD) are set to release the gene hacked ‘fraken-squitoes' in a bid to fight insect-borne viruses like yellow fever. A BILLION mutant mosquitoes are set to be released in the Keys to fight insect-borne viruses like yellow fever Florida pest ...
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Florida to release a billion genetically modified mosquitoes and people are worried

B. Robinson,  indy100,  2021.
It sounds like the pitch for a horror movie, but Florida’s about to release up to a billion genetically modified mosquitoes in the Keys. What could go wrong? Florida residents and environmentalists are already voicing their concerns after state officials and Oxitec, a ...
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Thousands of genetically modified mosquitoes being released in Florida

T. Lapin,  New York Post,  2021.
Thousands of genetically modified mosquitoes have begun to be released in Florida this week as part of an effort to combat a disease-spreading species of the insect. The buzzy project, from British biotech company Oxitec, aims to curb the population of Aedes aegypti mosquitoes, ...
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Halt This Nightmare’: Alarm as Florida Set to Begin Release of Genetically Engineered Mosquitoes

J. Johnson,  Common Dreams,  2021.
Environmentalists and Florida residents voiced concern and outrage Monday as state government officials and the biotechnology giant Oxitec announced plans to move ahead this week with a pilot project that involves releasing up to a billion genetically engineered mosquitoes in ...
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Florida residents claim ‘pest control trial’ that will release up to a BILLION genetically engineered mosquitos in the Keys to reduce species carrying diseases is ‘TERRORISM’

S. Liberatore,  Daily Mail,  2021.
The Florida Keys will soon be buzzing with close to a billion 'fraken-squitoes' – gene-hacked mosquitoes aimed at eradicating a disease carrying mosquito. The Florida Keys Mosquito Control District (FKMCD) and Oxitec, a British biotech company, are starting the first-ever U.S. ...
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Coalition Against GMO Mosquito Condemns Release of Genetically Engineered Mosquitoes

GMO Free USA,  3BL CSRwire,  2021.
Despite a decade of community opposition, the experimental release of genetically engineered mosquitoes begins today in the Florida Keys. British biotech corporation, Oxitec, in collaboration with the Florida Keys Mosquito Control District, plans to release up to a billion ...
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Nation’s First Trial Of Genetically Modified Mosquitoes Starts In Florida Keys

N. Klingener,  WLRN,  2021.
Boxes containing the eggs of genetically modified Aedes aegypti mosquitoes, water and a little food are being placed in six locations in the Lower and Middle Keys this week — in a trial that will be the first of its kind in the United States. The genetic modification is ...
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Does Gene Technology Offer Potential to Wipe Out Malaria?

Anonymous,  AFIDEP,  2021.
The persisting high numbers of Malaria deaths and illnesses mean that the current tools will not get us to zero Malaria. For this reason, experts have continued to explore new tools for Malaria elimination. The gene drive technology is one of the tools being explored for Malaria ...
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Fighting mosquitoes with mosquitoes

W. Feng,  The Daily Targum,  2021.
When you think about the animal that has killed the greatest number of humans in the world, you generally tend to think of large predators. Is it perhaps the great white shark or maybe the cute but deadly hippopotamus? While these animals are certainly deadly, the number of ...
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Quantifying the risk of vector-borne disease transmission attributable to genetically modified vectors

G. R. Hosack, A. Ickowicz and K. R. Hayes,  Royal Society Open Science,  8:201525. 2021.
The relative risk of disease transmission caused by the potential release of transgenic vectors, such as through sterile insect technique or gene drive systems, is assessed with comparison with wild-type vectors. The probabilistic risk framework is demonstrated with an assessment ...
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Hybrid mosquitoes? Evidence from rural Tanzania on how local communities conceptualize and respond to modified mosquitoes as a tool for malaria control

M. F. Finda, F. O. Okumu, E. Minja, R. Njalambaha, W. Mponzi, B. B. Tarimo, P. Chaki, J. Lezaun, A. H. Kelly and N. Christofides,  Malaria Journal,  20:134. 2021.
Different forms of mosquito modifications are being considered as potential high-impact and low-cost tools for future malaria control in Africa. Although still under evaluation, the eventual success of these technologies will require high-level public acceptance. Understanding ...
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Genetically modified mosquitoes for better health

D. Devis,  COSMOS,  2021.
One method of preventing these mosquito-born diseases is to use insecticides to kill the mozzies and remove them, but sometimes this only works as a short term solution, or has unintended devasting effects on the ecosystem. Another method for decreasing the number of ...
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Quantifying the risk of vector-borne disease transmission attributable to genetically modified vectors

G. R. Hosack, A. Ickowicz and K. R. Hayes,  Royal Society Open Science,  8:201525. 2021.
The relative risk of disease transmission caused by the potential release of transgenic vectors, such as through sterile insect technique or gene drive systems, is assessed with comparison with wild-type vectors. The probabilistic risk framework is demonstrated with an assessment ...
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Proceedings of an expert workshop on community agreement for gene drive research in Africa – Co-organised by KEMRI, PAMCA and Target Malaria [version 1; peer review: awaiting peer review]

D. Thizy, L. Pare Toe, C. Mbogo, D. Matoke-Muhia, V. P. Alibu, S. K. Barnhill-Dilling, T. Chantler, G. Chongwe, J. Delborne, L. Kapiriri, E. Nassonko Kavuma, S. Koloi-Keaikitse, A. Kormos, K. Littler, D. Lwetoijera, R. Vargas de Moraes, N. Mumba, L. Muten,  Gates Open Research,  2021.
Target Malaria, the Kenya Medical Research Institute and the Pan African Mosquito Control Association co-organised a workshop with researchers and practitioners on this topic to question the model proposed by Target Malaria in its research so far that involved the release of ...
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A patent review on strategies for biological control of mosquito vector

K. Parihar, M. Telang and A. Ovhal,  World Journal of Microbiology and Biotechnology,  36:23. 2020.
This paper presents a comprehensive technology overview of patent documents disclosing biological agents for mosquito control. The patent analysis revealed that comparable number of patent documents were filed in two technology categories: non-recombinant agents and genetically ...
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Mosquito transgenics and courtship songs

H. Hurd,  BugBitten BMC,  2020.
As a female flies into the swarm she is detected by the sound of her wing beat and males identify females by a phonotactic response to the specific sound frequency produced by her wing beat. A male and female will then attune to each other by altering the frequency of their ...
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Ethics and vector-borne diseases

WHO,  WHO Guidance,  2020.
The guidance was developed by an international group of experts in vector control, infectious disease ethics, maternal and child health, ecology and climate change, research and vaccine development, and public health communication. It examines a broad range of ethical ...
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Who is afraid of genetically modified mosquitoes?

G. Odogwu,  The PUNCH,  2020.
Genetically Modified Organisms have raised concerns in our clime, the same way they have in other countries of the world – where a clear line is drawn between the pro and the anti-GMO citizens. Nonetheless, this modern biotechnological technique is still at its infancy here. As ...
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Mosquito district workshop focuses on Keys trials

S. Matthis,  KEYSWEEKLY,  2020.
Now that the Oxitec “Friendly Mosquito” trials have been approved by the federal and state governments, it’s up to the Florida Keys Mosquito Control District to decide if, when and where to embrace the technology said to decrease the chances of mosquito-borne diseases such ...
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Genetically modified mosquitoes to be released in Florida and Texas

O. Ron,  The Jerusalem Post,  2020.
A plan to release 750 million genetically modified mosquitoes in Florida and Texas has been approved, The Guardian reported. According to the plan, the Aedes aegypti mosquitoes will be released into the wild, as they contain a special protein that would kill female offspring, ...
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Before genetically modified mosquitoes are released, we need a better EPA

N. Kofler and J. Kuzma,  The Boston Globe,  2020.
While the attention of the American public has rightfully been focused on the COVID-19 pandemic, its associated racial disparities, and broader issues of structural racism, the US government made a serious public health decision — one that could affect our health and our ...
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Are Genetically Modified Mosquitoes Coming To Florida?

M. Taylor,  Y100,  2020.
I'm not even going to lie, mosquitoes should be classified under domestic terrorism. The flying, biting bugs you can barely see wreak havoc on my life every single summer. I'm not sure if I'm allergic to them, but whenever I'm bit by them, that area of my skin swells up. It's the ...
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The Florida Keys are one step closer to getting genetically modified mosquitoes

D. Goodhue,  Miami Herald,  2020.
An international biotech company is one step closer to being able to release genetically modified mosquitoes in the Florida Keys. The Florida Department of Agriculture and Consumer Services this week granted Oxitec an experimental use permit to release potentially millions of ...
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The development of complex and controversial innovations. Genetically modified mosquitoes for malaria eradication

V. Cisnetto and J. Barlow,  Research Policy,  49:103917. 2020.
e use a longitudinal process approach and qualitative system dynamics modelling to study the development of genetically modified (GM) mosquitoes for malaria eradication in an African country.
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Two unresolved issues in community engagement for field trials of genetically modified mosquitoes

D. B. Resnik,  Pathogens and Global Health,  113:238-245. 2019.
There is an emerging consensus among scientists, ethicists, and public health officials that substantive and effective engagement with communities and the wider public is required prior to releasing genetically modified mosquitoes into the environment.
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For the first time, researchers will release genetically engineered mosquitoes in Africa

Ike Swetitz,  STAT,  2018.
The government of Burkina Faso granted scientists permission to release genetically engineered mosquitoes anytime this year or next, researchers announced Wednesday. It’s a key step in the broader efforts to use bioengineering to eliminate malaria in the region.
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Transgenic Mosquitoes – Fact or Fiction?

Wilke, A. B. B., J. C. Beier and G. Benelli,  Trends in Parasitology,  34:456-465. 2018.
echnologies for controlling mosquito vectors based on genetic manipulation and the release of genetically modified mosquitoes (GMMs) are gaining ground. However, concrete epidemiological evidence of their effectiveness, sustainability, and impact on the environment and nontarget ...
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Guidance framework for testing of genetically modified mosquitoes

WHO,  WHO-TDR,  2014.
As the research progresses, a need has been expressed both within the scientific community and by the public for additional standards and guidance. WHO-TDR and the Foundation for the National Institutes of Health (FNIH) co-sponsored a technical consultation meeting in 2009 to ...
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Ethical issues in field trials of genetically modified disease-resistant mosquitoes

D. B. Resnik,  Developing World Bioethics,  14:37-46. 2012.
Mosquito-borne diseases take a tremendous toll on human populations, especially in developing nations. In the last decade, scientists have developed mosquitoes that have been genetically modified to prevent transmission of mosquito-borne diseases, and field trials have been ...
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Why RIDL is not SIT

W. C. Black, L. Alphey and A. A. James,  Trends in Parasitology,  27:362-370. 2011.
History teaches that sterile insect technique (SIT) is a feasible strategy for mosquito population suppression. Female killing (FK) technologies developed later theoretically had greater potential than SIT, but depended upon chromosomal translocations. Unfortunately these were ...
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First Anopheles arabiensis germline transformation: Toward the development of a transgenic genetic sexing strain

H. C. Bossin, J. Thailayil, F. Catteruccia, J. P. Benton, A. Crisanti, M. Q. Benedict, B. G. Knols and A. S. Robinson,  American Journal of Tropical Medicine and Hygiene,  75:66-66. 2006.
The ability to genetically engineer mosquitoes is likely to have major implications for the development and implementation of genetic control systems against mosquito disease vectors such as the Sterile Insect Technique (SIT). In particular, genetically transformed mosquito ...
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