Scholarly Literature

This is a database of scholarly literature that concentrates currently on natural and engineered selfish genetic elements (gene drives).  The latest are shown here.
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Resistance to meiotic drive at MD locus in an Indian wild population of Aedes aegypti

Suguna, SGW, R. J.; Curtis, C. F.; Whitelaw, A.; Kazmi, S. J.,  Genetical Research,  29:123-132. 1977.
Females from an Indian wild population of Aedes aegypti were crossed to males carrying the sex ratio distorter factor MB which shows meiotic drive. Progenies from ¥1 males were tested for sex ratio distortion, i.e. the chromosomes from the wild females were screened for their ...
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Experimental population-genetics of meiotic drive systems .1: Pseudo-Y chromosomal drive as a means of eliminating cage populations of Drosophila melanogaster

Lyttle, TW,  Genetics,  86:413-445. 1977.
The experimental population genetics of Y-chromosome drive in Drosophila; melanogasier is approximated by studying the behavior of T(Y;S),SD lines.; These exhibit “pseudo-Y” drive through the effective coupling of the Y chromosome; to the second chromosome meiotic drive ...
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Field trial of competitive displacement of Aedes-polynesiensis by Aedes-albopictus on a Pacific atoll

L. Rosen, L. E. Rozeboom, W. C. Reeves, J. Saugrain and D. J. Gubler,  American Journal of Tropical Medicine and Hygiene,  25:906-913. 1976.
Prior laboratory studies and field observations suggested that it might be possible to reduce the size of the population of, or eliminate, Aedes polynesiensis by the introduction of Aedes albopictus. The former mosquito is the principal vector of nonperiodic filariasis caused by ...
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Between family variation in sex-ratio in Trinidad (T-30) strain of Aedes-aegypti (L) indicating differences in sensitivity to meiotic drive gene MD

Wood, RJ,  Genetica,  46:345-361. 1976.
Sex ratio in the Trinidad (T-30) strain of Aedes aegypti has remained constant at around 43%? during seventeen years of laboratory culture. The divergence from 50% is due to meiotic drive by the MD gene on the Y chromosome. The driving Y chromosome gives a much more distorted sex ...
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Population genetics of modifiers of meiotic drive.3. Equilibrium analysis of a gneral model for genetic control of segregation distortion

Thomson, GJF, M. W.,  Theoretical Population Biology,  10:8-25. 1976.
Prout, Bungaard and Bryant (1973, Theor. Popul. Biol. 4, 446–465) presented the first formal treatment of a model of meiotic drive involving a modifier locus which controls the intensity of drive. They studied the equilibrium behavior in the simplest model where it is assumed ...
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Evidence for autosomal meiotic drive in the butterfly Danaus chrysippus L.

Smith, DAS,  Heredity,  36:139-142. 1976.
Danaus chrysippus (Danaidae) in East Africa is highly polymorphic for colour, the genetic control of which resides at three loci. The B locus has two alleles, B giving a nutbrown ground colour and bb orange on both fore and hindwings. The C locus determines forewing pattern: ...
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Cytogenetic analysis of meiotic drive in mosquito, Aedes aegypti

Newton, MEW, R. J.; Southern, D. I.,  Genetica,  46:297-318. 1976.
Meiotic drive in Aedes aegypti (L.) is shown by a Giemsa C-banding technique to be associated with. preferential isochromatid breakage of the X chromosome during male meiosis. These breaks remain open at least until anaphase-I and, since the range of cells affected is ...
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Population replacement in Culex-fatigans by means of cytoplasmic incompatibility .2. Field cage experiments with overlapping generations

C. F. Curtis,  Bulletin of the World Health Organization,  53:107-119. 1976.
Three experiments were carried out in field cages to test the principle of " transport" of a desirable gene or chromosome into a wild Culex fatigans population as a result of the sterility in cross-matings associated with cytoplasmic incompatibility. Cycling populations of Delhi ...
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Modifier theory of meiotic drive: Is Mendelial segregation stable

Liberman, U,  Theoretical Population Biology,  10:127-132. 1976.
The evolutionary fate of rare modifiers, based on the modifier theory of meiotic drive, is studied in this paper. It is shown that a polymorphism based on Mendelian segregation is never stable for any recombination frequencies between 0 and 12, and that, for tight linkage between ...
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Meiotic drive for B-chromosomes in primary oocytes of Myrmeleotettix maculatus (Orthoptera-Acrididae)

Hewitt, GM,  Chromosoma,  56:381-391. 1976.
Using a modified technique which allowed observation of chromosome orientation in the primary oocyte of grasshoppers at the onset of anaphase, it has been possible to establish that the B-chromosome is distributed preferentially on the egg side of the metaphase plate rather than ...
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Population genetics of modifiers of meiotic drive 4: Evolution of sex-ratio distortion

Thomson, GJF, M. W.,  Theoretical Population Biology,  8:202-211. 1975.
A model for the evolution of the sex-ratio meiotic drive system in Drosophila is proposed and analyzed. The model incorporates drive and altered fertility genetic modification The condition change in the sex-ratio of the modifying distortion overcome any relative of meiotic in ...
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Sex-chromosome meiotic drive systems in Drosophila melanogaster .1: Abnormal spermatid development in males with a heterochromatin-deficient X-chromosome (sc4sc8)

Peacock, WJM, G. L. G.; Goodchild, D. J.,  Genetics,  79:613-634. 1975.
The meiotic drive characteristics of the In(1)sc4Lsc8R/Y system have been examined by genetic analysis and by light and electron microscopy. sc4sc8/Y males show a direct correlation between nondisjunction frequency and meiotic drive. Temperature-shift experiments reveal that the ...
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Modifier theory of meiotic drive

Hartl, DL,  Theoretical Population Biology,  7:168-174. 1975.
The evolutionary fate of rare modifiers of recessive lethal segregation distorters has been studied. Suppressors or partial suppressors will always increase in frequency. Enhancers will increase in frequency if linkage is sufficiently tight and be lost if linkage is sufficiently ...
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Sex-ration, meiotic drive, and group selectin in Drosophila pseudoobscura

Policansky, D,  American Naturalist,  108:75-90. 1974.
Sex ratio (SR) is a widespread genetic condition of the X-chromosome in Drosophila species which causes males to produce progenies consisting almost entirely of females. Results of samples from natural populations of Drosophila pseudoobscura and results of some laboratory ...
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Population replacement in Culex fatigens by means of cytoplasmic incompatibility. Laboratory experiments with non-overlapping generations

C. F. Curtis and T. Adak,  Bulletin of the World Health Organization,  51:249-255. 1974.
Bidirectional cytoplasmic incompatibility in the Culex pipiens complex appears to provide a mechanism for the replacement of a wild population by a strain refractory to filaria or a strain made partly sterile by a translocation. As a preliminary test of the feasibility of the ...
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Genetic control of insect populations: I. Cage studies of chromosome replacement by compound autosomes in Drosophila melanogaste

M. Fitz-Earle, D. G. Holm and D. T. Suzuki,  Genetics,  74:461-475. 1973.
A genetic method for insect control was evaluated using the test organism, Drosophila melanogaster. The technique involved the displacement under a system of continuous reproduction, of standard strains by those carrying compound autosomes. The eradication of the replacements ...
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Changing population structure through the use of compound chromosomes

D. Childress,  Genetics,  72:183-186. 1972.
Theoretical calculations and population cage data are presented to illustrate the use of compound chromosomes to change the genetic structure of insect populations.
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Chromosome rearrangements for the control of insect pests

G. G. Foster, M. J. Whitten, T. Prout and R. Gill,  Science,  176:875-880. 1972.
Over several years some biologists have been interested in the possibilities of employing genetic techniques in the control of insect pests. One idea has been to introduce in the natural population genotypes which could subsequently facilitate control, or which might render the ...
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Multiple meiotic drive systems in Drosophila melanogaster male

Miklos, GLGY, A. F.; Peacock, W. J.,  Genetics,  72:105-115. 1972.
The behaviour of two "meiotic drive" systems, Segregation-Distorter (SD) and the sex chromosome sc4sc8 has been examined in the same meiocyte. It has been found that the two systems interact in a specific way. When the distorting effects of SD and sc4sc8 are against each other, ...
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Insect control by genetic manipulation of natural populations

M. J. Whitten,  Science,  171:682. 1971.
The possible use of chromosome rearrangements is considered as a means for introducing genes into insect populations for their own control. The release of laboratory-constructed strains differing from the field population for a number of chromosome interchanges should create an ...
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