Keywords: SIT

Predicting the spread and persistence of genetically modified dominant sterile male mosquitoes

A. Ickowicz, S. D. Foster, G. R. Hosack and K. R. Hayes,  Parasites and Vectors,  14:480. 2021.
Reproductive containment provides an opportunity to implement a staged-release strategy for genetic control of malaria vectors, in particular allowing predictions about the spread and persistence of (self-limiting) sterile and male-biased strains to be compared to outcomes before ...
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Mosquitoes Sterilized by CRISPR Powered Precision System

A. A. Sarkar,  Genetic Engineering & Biotechnology News,  2021.
Each year millions around the world are infected by dengue, chikungunya, and Zika viruses. The principal culprit behind the transmission of these deadly diseases is the mosquito vector, Aedes aegypti. Conventional methods of pest control have so far fallen short. To curb the ...
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New precision-guided sterile insect technique designed to control disease-spreading mosquitoes

E. Henderson,  News Medical Life Sciences,  2021.
Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases. The new precision-guided sterile ...
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Genetic engineering tech promises to sterilize disease-spreading mosquitoes

B. Hays,  UPI,  2021.
Inspired by improvements in CRISPR-based genetic engineering, scientists have developed a more precise insect sterilization system to curtail, or even eliminate, disease-spreading Aedes aegypti mosquito populations. The so-called "precision-guided sterile insect technique," or ...
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Genetic Engineering Technology Promises To Sterilize Disease-Spreading Mosquito Populations

D. Gyllhem,  VIGOURTIMES,  2021.
Inspired by improvements in CRISPR-based genetic engineering, scientists have developed a more precise insect sterilization system to curtail, or even eliminate, disease-spreading Aedes aegypti mosquito populations. The so-called “precision-guided sterile insect technique,” ...
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New Technology Designed to Genetically Control Disease-spreading Mosquitoes

M. Aguilera,  UC San Diego News Center,  2021.
Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases. An illustration by study coauthor ...
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Suppressing mosquito populations with precision guided sterile males

M. Li, T. Yang, M. Bui, S. Gamez, T. Wise, N. P. Kandul, J. Liu, L. Alcantara, H. Lee, J. R. Edula, R. Raban, Y. Zhan, Y. Wang, N. DeBeaubien, J. Chen, H. M. Sánchez C, J. B. Bennett, I. Antoshechkin, C. Montell, J. M. Marshall and O. S. Akbari,  Nature Communications,  12:5374. 2021.
The mosquito Aedes aegypti is the principal vector for arboviruses including dengue/yellow fever, chikungunya, and Zika virus, infecting hundreds of millions of people annually. Unfortunately, traditional control methodologies are insufficient, so innovative control methods are ...
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Genetically Modified Mosquitoes — What’s The Real Story?

SPW Staff,  Southeast Product Weekly,  2021.
You’ve heard about the genetically modified mutant mosquitoes being released in the Florida Keys — but what exactly is going on, and how, and why? Basically, researchers in parts of the Florida Keys are releasing male mosquitoes that have been genetically modified to produce ...
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UF/IFAS Researchers Explain Science Behind Genetically Modified Mosquitoes

PCT Staff,  Pest Control Technology,  2021.
South Florida residents seeking science-based information about genetically modified mosquitoes can access a new, online resource from University of Florida scientists at the UF/IFAS Florida Medical Entomology Laboratory.“ Genetically Modified Mosquitoes” is the latest ...
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New Way to Reduce Diseases Spreading Through Mosquitos

Dr Jayashree,  Medindia,  2021.
Using a gene editing tool known as CRISPR-Cas9 that targets specific genes tied to fertility in male mosquitoes, we can slow the spread of potentially deadly diseases such as Zika, dengue fever and yellow fever. This genome editing tool is creating a buzz in the science world, as ...
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Gene Editing Could Render Mosquitos Infertile

U.S. Army DEVCOM Army Research Laboratory Public Affairs,  U.S. Army,  2021.

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Genetically Modified Mosquitoes

E. P. Caragata, Y. Lee and E. A. Buckner,  UF IFAS Extension Service,  2021.
Genetically modified (GM) mosquitoes are controversial, partly because of misinformation. This publication provides science-based information about GM mosquitoes to the public and anyone involved in mosquito control. It explains what GM mosquitoes are and why they are being ...
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A Monte Carlo study to investigate the feasibility to use the Moroccan panoramic irradiator in sterile insect technique programs

A. Aknouch, Y. El-ouardi, L. Hamroud, R. Sebihi, M. Mouhib, M. Yjjou, A. Didi and A. Choukri,  Radiation and Environmental Biophysics,  2021.
Mediterranean fly pest (Ceratitis) is one of the most destructive pests of fruit species in Morocco. The sterile insect technique (SIT) is an environmentally friendly strategy that uses ionizing radiation to sterilize adult insects. Morocco has a panoramic gamma irradiator used ...
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Oxitec eyes California for its next GM mosquito pilot projec

J. Conrow,  ,  2021.
Buoyed by its success in the Florida Keys, Oxitec Ltd. is now looking to California to test its program for controlling mosquito pests through genetic engineering, rather than insecticides. The field research is intended to show that genetically modified (GM) mosquitoes are a ...
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Oxitec Advances Process to Bring Friendly™ Mosquito Technology to California to Help Government Agencies Protect Public Health

Oxitec,  Oxitec,  2021.
Following successful launch of its Friendly™ Aedes aegypti pilot program in the Florida Keys, Oxitec, the leading developer of biological solutions to control pests that transmit disease, destroy crops and harm livestock, has requested approval from the U.S. Environmental ...
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Transgenic expression of Nix converts genetic females into males and allows automated sex sorting in Aedes albopictus

C. Lutrat, R. P. Olmo, T. Baldet, J. Bouyer and E. Marois,  bioRxiv,  2021.07.28.454191. 2021.
Aedes albopictus is a major vector of arboviruses. Better understanding of its sex determination is crucial for developing mosquito control tools, especially genetic sexing strains. In Aedes aegypti, Nix is the primary gene responsible for masculinization and Nix-expressing ...
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Sex separation of Aedes spp. mosquitoes for sterile insect technique application: a review

B. M. Moran-Aceves, C. F. Marina, A. Dor, P. Liedo and J. Toledo,  Entomologia Experimentalis Et Applicata,  10. 2021.
Separation of the sexes is necessary for the application of the sterile insect technique (SIT) in mosquitoes due to the hematophagous habits and disease vector activity of the females. In this review we analyze the history, current status, and future perspectives for the ...
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Using Moderate Transgene Expression to Improve the Genetic Sexing System of the Australian Sheep Blow Fly Lucilia cuprina

Y. Yan, M. E. Williamson and M. J. Scott,  Insects,  11. 2021.
The sterile insect technique (SIT) is a promising strategy to control the Australian sheep blow fly Lucilia cuprina, a major pest of sheep. We have previously developed a transgenic embryonic sexing system (TESS) for this pest to facilitate the potential SIT application. TESS ...
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The Possible Role of Microorganisms in Mosquito Mass Rearing

L. Chersoni, A. Checcucci, M. Malfacini, A. Puggioli, F. Balestrino, M. Carrieri, I. Piunti, M. L. Dindo, P. Mattarelli and R. Bellini,  Insects,  12. 2021.
In Europe, one of the most significant mosquitoes of public health importance is Aedes albopictus (Skuse), an allochthonous species of Asian origin. One of the most promising control methods against Aedes albopictus is the sterile insect technique (SIT), which consists of mass ...
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Sterile Insect Technique (SIT) and Its Applications

K. Bourtzis and M. J. B. Vreysen,  Insects,  12. 2021.
Although most insect species have a beneficial role in the ecosystems, some of them represent major plant pests and disease vectors for livestock and humans. During the last six–seven decades, the sterile insect technique (SIT) has been used as part of area-wide integrated pest ...
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Unique effort underway to control deadly mosquitos in Florida Keys

K. Corso and L. Aguirre,,  2021.
According to the World Health Organization, more than 50% of the world’s population is under the threat of mosquito borne diseases. In South Florida, the Keys are a hot spot for infection and now the first place in the United States for a novel approach to eradicating these ...
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Improvement of the Mass-Rearing Protocols for the South American Fruit Fly for Application of the Sterile Insect Technique

T. Mastrangelo, A. Kovaleski, B. Maset, M. D. Costa, C. Barros, L. A. Lopes and C. Caceres,  Insects,  12. 2021.
The existing rearing protocols for Anastrepha fraterculus must be reviewed to make economically viable the production of sterile flies for their area-wide application. Additionally, evidence of sexual incompatibility between a long-term mass-reared Brazilian strain and wild ...
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Comparative response to post-production process of two Anastrepha ludens strains: Application in the sterile insect technique

J. Arredondo, J. F. Aguirre-Medina, J. S. Meza, J. Cancino and F. Diaz-Fleischer,  Journal of Applied Entomology,  11. 2021.
The new desiccation-resistant (DR) strain of Anastrepha ludens Loew differs in its life-history traits from the non-selected strain (NS). Given the innate resistance of DR flies to stressors, it is necessary to determine the packing and shipment conditions for their use in the ...
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Effect of the timing of pupal irradiation on the quality and sterility of oriental fruit flies (Diptera: Tephritidae) for use in Sterile Insect Technique

T. J. Fezza, P. A. Follett and T. E. Shelly,  Applied Entomology and Zoology,  8. 2021.
The Sterile Insect Technique (SIT) is a target-specific, biologically based method used to control pestiferous tephritids entailing the release of mass-reared, sterilized males of the target species to achieve sterile male x wild female matings. As documented for several ...
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Remating in Ceratitis capitata sterile males: Implications in sterile insect technique programmes

M. Catala-Oltra, E. Llacer, O. Dembilio, I. Pla, A. Urbaneja and M. Perez-Hedo,  Journal of Applied Entomology,  8. 2021.
Sterile insect technique (SIT) is used, among other biological control tools, as a sustainable measure for the management of Ceratitis capitata Wiedemann (Diptera: Tephritidae) in many agricultural regions where this pest can trigger severe economic impacts. The tendency of wild ...
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A transgenic female killing system for the genetic control of Drosophila suzukii

M. F. Schetelig, J. Schwirz and Y. Yan,  Scientific Reports,  11:12938. 2021.
The spotted wing Drosophila (Drosophila suzukii) is an invasive pest of soft-skinned fruit crops. It is rapidly transmitted in Europe and North America, causing widespread agricultural losses. Genetic control strategies such as the sterile insect technique (SIT) have been ...
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Why Flight Testing is an Important Step in Sterile Insect Technique

E. Ricciuti,  Entomology Today,  2021.
Releasing hordes of sterilized male insects for unfruitful mating with females—a process known as the sterile insect technique (SIT)—is a proven process for combating many species of pests. Its success depends on sterile males dispersing widely enough to outcompete their wild ...
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Why Are Gates and Pentagon Releasing GMO Mosquitoes in Florida Keys?

F. W. Engdahl,,  2021.
On April 30 the Florida Keys Mosquito Control District and the Oxitec biotechnology company announced they will begin release of what will ultimately be some 750 million genetically manipulated or gene-edited Aedes Aegypti mosquitos using CRSPR gene editing technology. The Aedes ...
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Genetically Modified Mosquitoes; ‘Truth Like Oil’ Novel

Here and Now,  WBUR,  2021.
Florida Keys officials are working on a unique experiment: hatching thousands of genetically modified mosquitos and releasing them. Andrea Leal of the Florida Keys Mosquito Control District explains.
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Temperature-Inducible Precision Guided Sterile Insect Technique

N. P. Kandul, J. Liu and O. S. Akbari,  bioRxiv,  2021.06.14.448312. 2021.
Releases of sterile males are the gold standard for many insect population control programs, and precise sex sorting to remove females prior to male releases is essential to the success of these operations. To advance traditional methods for scaling the generation of sterile ...
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The First Genetically Modified Mosquitoes Have Just Been Released in The US

Admin,  Science World,  2021.
The biotech firm Oxitec has released its genetically modified mosquitoes in the Florida Keys, with the goal of suppressing wild, disease-carrying mosquito populations in the region. This is the first time genetically modified mosquitoes have been released in the US. Oxitec ...
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Bill Gates Releasing Genetically Modified Mosquitoes in Florida? Here’s the Whole Story

M. Dapcevich,  Snopes,  2021.
Bill Gates is not himself releasing mosquitoes into the wild. However, the Bill and Melinda Gates Foundation did award grants that funded biotech company Oxitec's work to develop genetically modified mosquitoes that may help reduce the spread of malaria and other mosquito-borne ...
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Mutant mosquitoes carrying ‘death gene’ released as ‘bio-engineered’ insects terrify

J. Caven,  Daily Star,  2021.
Mutant mosquitoes which carry a ‘death gene’ have been released into the skies in a bid to curb diseases from spreading to humans. Tens of thousands of genetically modified male insects will mate with female Aedes aegypti mosquitoes, which transmit illnesses, in Florida ...
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Genetically Altered Mosquitoes Target Deadly Dengue Fever and Zika

R. L. Hotz,  Wall Street Journal,  2021.