Scholarly Literature

This is a database of scholarly literature that concentrates currently on natural and engineered selfish genetic elements (gene drives).  The latest are shown here.
Disclaimer>

Invasive Species Control and Resolution of Wildlife Damage Conflicts: A Framework for Chemical and Genetically Based Management Methods

Tags: , , , , , , , ,
L. Clark, J. Eisemann, J. Godwin, K. E. Horak, K. Oh, J. O’Hare, A. Piaggio, K. Pepin and E. Ruell,  GMOs: Implications for Biodiversity Conservation and Ecological Processes,  2020.
Vertebrate wildlife damage management relates to developing and employing methods to mitigate against damage caused by wildlife in the areas of food production, property damage, and animal or human health and safety. Of the many management tools available

GMOs: Implications for Biodiversity Conservation and Ecological Processes

Tags: , , , , , ,
Chaurasia, Anurag , Hawksworth, David L., Pessoa de Miranda, Manoela.,  GMOs: Implications for Biodiversity Conservation and Ecological Processes,  2020.
This book covers a broad spectrum of topics related to GMOs and allied new gene-based technologies, biodiversity, and ecosystem processes, bringing together the contributions of researchers and regulators from around the world. The aim is to offer a clear view of the benefits and ...

Modelling the Wolbachia incompatible insect technique: strategies for effective mosquito population elimination

Tags: , , , , , , ,
D. E. Pagendam, B. J. Trewin, N. Snoad, S. A. Ritchie, A. A. Hoffmann, K. M. Staunton, C. Paton and N. Beebe,  BMC Biology,  18:13. 2020.
We introduce a simple Markov population process model for studying mosquito populations subjected to a Wolbachia-IIT programme which exhibit an unstable equilibrium threshold. The model is used to study, in silico, scenarios that are likely to yield a successful elimination ...

Mosquito genomes are frequently invaded by transposable elements through horizontal transfer

Tags:
E. S. de Melo and G. L. Wallau,  PLOS Genetics,  16:e1008946. 2020.
We characterized the whole TE content of 24 mosquito genomes and investigated the TE inheritance mode uncovering hundreds of horizontal transfer events among these species and distantly related ones. We also identify a mosquito parasitic filarial worm, th

Strategic Approach, Advances, and Challenges in the Development and Application of the SIT for Area-Wide Control of Aedes albopictus Mosquitoes in Reunion Island

Tags: , ,
L. C. Gouagna, D. Damiens, C. F. Oliva, S. Boyer, G. Le Goff, C. Brengues, J.-S. Dehecq, J. Raude, F. Simard and D. Fontenille,  Insects,  11:770. 2020.

Reply to: “Enhancement of Aedes aegypti susceptibility to dengue by Wolbachia is not supported”

Tags: , , , , , ,
C. Souto-Maior, J. G. King, L. M. Sartori, R. Maciel-de-Freitas and M. G. M. Gomes,  Nature Communications,  11:6113. 2020.
Ant et al.4 claim that concerns with the data and broader analysis make our conclusions misleading. We herein respond to their comments by demonstrating the robustness of our results to different treatments of the data, and expand our arguments for replacing currently adopted ...

Enhancement of Aedes aegypti susceptibility to dengue by Wolbachia is not supported

Tags: , , , , , ,
T. H. Ant, M.-V. Mancini, J. Martinez and S. P. Sinkins,  Nature Communications,  11:6111. 2020.
King et al.3 used DENV infection and transmission modelling to reinterpret experimental data from two previous studies4,5. The authors claimed that wMel Wolbachia increase the mean susceptibility of Ae. aegypti to DENV, contradicting various other studies6,7,8,9,10,11,12. Here, ...

Toxin-Antidote Elements Across the Tree of Life

A. Burga, E. Ben-David and L. Kruglyak,  Annual Review Genetics,  54:387-415. 2020.
Toxin-antitoxin or toxin-antidote (TA) elements are genetic dyads that cheat the laws of inheritance to guarantee their transmission to the next generation. This seemingly simple genetic arrangement-a toxin linked to its antidote-is capable of quickly spreading and persisting in ...

Combined Effects of Mating Disruption, Insecticides, and the Sterile Insect Technique on Cydia pomonella in New Zealand

Tags: , , ,
R. M. Horner, P. L. Lo, D. J. Rogers, J. T. S. Walker and D. M. Suckling,  Insects,  11:23. 2020.
We aimed to supplement these tactics with the sterile insect technique (SIT) to further suppress the codling moth on orchards. SIT involves mass rearing and sterilizing codling moth and then releasing them onto orchards where they mate with wild insects resulting in no offspring. ...

Split drive killer-rescue provides a novel threshold-dependent gene drive

Tags: , , , , , , , , ,
M. P. Edgington, T. Harvey-Samuel and L. Alphey,  Scientific Reports,  10. 2020.
Population genetics mathematical models are developed here to demonstrate the threshold-dependent nature of the proposed system and its robustness to imperfect homing, incomplete penetrance of toxins and transgene fitness costs, each of which are of practical significance given ...

Transformation and slippage in co-production ambitions for global technology development: The case of gene drive

Tags: , , , ,
K. Ledingham and S. Hartley,  Environmental Science & Policy,  116:78-85. 2020.
Co-production is an increasingly popular framework for knowledge generation, evaluation and decision making. Despite its potential to open up decisions and practices to the input of others, co-production regularly falls short of its transformative ambitions. Through documentary ...

Field Competitiveness of Aedes albopictus (Diptera: Culicidae) Irradiated Males in Pilot Sterile Insect Technique Trials in Northern Italy

Tags: ,
R. Bellini, M. Carrieri, F. Balestrino, A. Puggioli, M. Malfacini and J. Bouyer,  Journal of Medical Entomology,  58:807-813. 2020.
Vector-borne diseases account for 17% of infectious diseases, leading to more than one million deaths each year. Mosquitoes are responsible for 90% of the casualties and alternative control methods to insecticides are urgently needed, especially against Aedes vectors. Aedes ...

Sequence analysis in Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages

Tags: , ,
J. F. Hughes, H. Skaletsky, T. Pyntikova, N. Koutseva, T. Raudsepp, L. G. Brown, D. W. Bellott, T.-J. Cho, S. Dugan-Rocha, Z. Khan, C. Kremitzki, C. Fronick, T. A. Graves-Lindsay, L. Fulton, W. C. Warren, R. K. Wilson, E. Owens, J. E. Womack, W. J. Murphy,  Genome Research,  2020.
Here, we provide evidence that suppression of X–Y crossing-over unleashed a second dynamic: selfish X–Y arms races that reshaped the sex chromosomes in mammals as different as cattle, mice, and men. Using super-resolution sequencing, we explore the Y Chromosome of Bos taurus ...

Engineering biological diversity: the international governance of synthetic biology, gene drives, and de-extinction for conservation

Tags: , , , , , ,
J. L. Reynolds,  Current Opinion in Environmental Sustainability,  49:1-6. 2020.
In the face of insufficient progress in conserving and restoring biodiversity, the in situ use of advanced genetic modification, gene drives, and other biotechnologies for conservation purposes are being considered, researched, and developed. This paper introduces the methods, ...

Assessment of a Novel Adult Mass-Rearing Cage for Aedes albopictus (Skuse) and Anopheles arabiensis (Patton).

Tags: , , , ,
H. Maïga, W. Mamai, N. S. Bimbilé Somda, T. Wallner, B. S. Poda, G. Salvador-Herranz, R. Argiles-Herrero, H. Yamada and J. Bouyer,  Insects,  11:801. 2020.
Successful implementation of the sterile insect technique (SIT) against Aedes albopictus and Anopheles arabiensis relies on a continuous supply of sterile males. To meet this requirement, optimization of the mass-rearing techniques is needed. This study, therefore, aims to assess ...

Gene drives, species, and compassion for individuals in conservation biology

Tags: , , , , , , ,
Y. Rohwer,  Ethics, Policy and Environment,  2020.
In this paper I argue that these compassionate conservationists have a moral obligation to support the investigation and development of genetic modification technologies because of their potential to minimize suffering and eliminate killing in conservation. Furthermore, I will ...

When Extinction is Warranted: Invasive Species, Suppression-Drives, and the Worst-Case Scenario

Tags: , , , , , ,
A. C. Thresher,  Ethics, Policy and Environment,  2020.
The focus of this paper is on one such risk ? the danger of a suppression-drive escaping containment and wiping out the target species globally. Here, I argue that in most cases this risk is significant enough to warrant holding off on the technology. In some cases, however, we ...

Modeling CRISPR gene drives for suppression of invasive rodents

Tags: , , , , ,
S. E. Champer, N. Oakes, R. Sharma, P. García-Díaz, J. Champer and P. W. Messer,  bioRxiv,  2020.11.05.369942. 2020.
Here, we develop a high-fidelity model of an island population of invasive rodents that includes three types of suppression gene drive systems. The individual-based model is spatially explicit and allows for overlapping generations and a fluctuating population size. Our model ...

A gene-drive rescue system for the modification of malaria mosquito populations

Tags: , , , , , ,
A. Adolfi,  Nature Research Bioengineering Community,  2020.
Mosquito populations can now be reliably modified using 1) antimalarial molecules that block parasite development and 2) a CRISPR-based gene drive system that mediates their rapid spreading across the vector population.

A test for meiotic drive in hybrids between Australian and Timor zebra finches

Tags: , ,
U. Knief, W. Forstmeier, Y. Pei, J. Wolf and B. Kempenaers,  Ecology and Evolution,  2020.
We did not find evidence for meiotic driver loci on specific chromosomes. However, we observed a weak overall transmission bias toward Timor alleles at centromeres in females (transmission probability of Australian alleles of 47%, nominal p = 6 ? 10?5). While this is in line ...

« First ‹ Previous 1 55 63 64 65 66 67 75 118 Next › Last »