Keywords: rodents
|
Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning frameworkS. E. Champer, N. Oakes, R. Sharma, P. García-Díaz, J. Champer and P. W. Messer, PLoS Comput Biol, 17:e1009660. 2021.
Invasive rodent populations pose a threat to biodiversity across the globe. When confronted with these invaders, native species that evolved independently are often defenseless. CRISPR gene drive systems could provide a solution to this problem by spreading transgenes among ... |
|
To exterminate, or not to: Scientists debate tweaking wild genomesFrench Press Agency, Daily Sabah, 2021.
veryone remembers Jeff Goldblum's famous speech in 1993 classic Jurassic Park: “Your scientists were so preoccupied with whether they could, they didn't stop to think if they should.” Well, these scientists are debating whether one should. In the movie, reconstructing and ... |
|
Scientists debate promise, peril of tweaking wild genomesJ. Zamora, Phys Org, 2021.
In the movie Jurassic Park, reconstructing and tweaking genetic material makes it possible to bring dinosaurs back to life. Today, a technology that manipulates animal genomes, called gene drive, has become a reality. The goal, however, is not to revive long-gone species, but to ... |
|
The New Yorker Magazine: Gene Drives as a Tool for Saving NatureE. Heber, Island Conservation, 2021.
In a recent New Yorker Magazine article, entitled “CRISPR and the Splice to Survive,” journalist and best-selling author Elizabeth Kolbert dives into the world of gene drive research. She touches on aspects of gene drive research from altering the toxin produced by cane toads ... |
|
Modeling CRISPR gene drives for suppression of invasive rodentsS. E. Champer, N. Oakes, R. Sharma, P. García-Díaz, J. Champer and P. W. Messer, bioRxiv, 2020.11.05.369942. 2020.
Here, we develop a high-fidelity model of an island population of invasive rodents that includes three types of suppression gene drive systems. The individual-based model is spatially explicit and allows for overlapping generations and a fluctuating population size. Our model ... |
