Scholarly Literature • GeneConvene Virtual Institute

This is an aggregation of scholarly literature from peer-reviewed journals, bioRxiv , medRxiv and arXiv preprint serversfocused on natural and engineered selfish genetic elements and genetic biocontrol. New citations are added as they appear. This content is intended for anyone interested in the scholarly literature on gene drive and genetic biocontrol.

View all Scholarly Literature > | Search the knowledgebase > | Disclaimer >

	A model-informed target product profile for population modification gene drives for malaria control Agastya Mondal, Héctor M. Sánchez C., John M. Marshall, medRxiv, 2024. As reductions in malaria transmission in sub-Saharan Africa stagnate, gene drive-modified mosquitoes represent one of the most promising novel tools for continued disease control. In order to advance from the laboratory to the field, gene drives will be assessed against target ...
	Autosomal suppression of sex-ratio meiotic drive influences the dynamics of X and Y chromosome coevolution Anjali Gupta, Robert L Unckless, Journal of Heredity, 2024. Sex-ratio meiotic drivers are selfish genes or gene complexes that bias the transmission of sex chromosomes resulting in skewed sex ratios. Existing theoretical models have suggested the maintenance of a four-chromosome equilibrium (with driving and standard X and suppressing and ...
	Bunyamwera Virus Infection of Wolbachia-Carrying Aedes aegypti Mosquitoes Reduces Wolbachia Density Lefteri, D.A.; Rainey, S.M.; Murdochy, S.M.; Sinkins, S.P., Viruses, 16. 2024. Wolbachia symbionts introduced into Aedes mosquitoes provide a highly effective dengue virus transmission control strategy, increasingly utilised in many countries in an attempt to reduce disease burden. Whilst highly effective against dengue and other positive-sense RNA viruses, ...
	Functional and evolutionary constraints of wtf killer meiotic drivers Ananya Nidamangala Srinivasa, Samuel Campbell, Shriram Venkatesan, Nicole L Nuckolls, Jeffrey J Lange, Randal Halfmann, Sarah E Zanders, bioRxiv, 2024. Killer meiotic drivers are selfish DNA loci that sabotage the gametes that do not inherit them from a driver+/driver- heterozygote. These drivers often employ toxic proteins that target essential cellular functions to cause the destruction of driver- gametes. Identifying the ...