Scholarly Literature
This is an aggregation of scholarly literature from peer-reviewed journals, bioRxiv , medRxiv and arXiv preprint servers focused on natural and engineered selfish genetic elements and genetic biocontrol. New citations are added as they appear. This content is intended for anyone interested in the scholarly literature on gene drive and genetic biocontrol.
A selfish supergene causes meiotic drive through both sexes in Drosophila
Tags: Fruit fly, Selfish genetic elements, X chromosomeG.L. Keais,C.M. Saad-Roy,E. Gonzalez-Sqalli, et al., Proceedings of the National Academy of Sciences, 122. 2025.
Meiotic drivers are selfish genetic elements that bias their own transmission during meiosis or gamete formation. Due to the fundamental differences between male and female meiosis in animals and plants, meiotic drivers operate through distinct mechanisms in the two sexes: In ...
Optimization of SgRNA expression with RNA pol III regulatory elements in Anopheles stephensi
Tags: Anopheles, CRISPR, Genetic biocontrol, Malaria, MosquitoesGonzalez, E., Anderson, M.A.E., Ang, J.X.D. et al., Scientific Reports, 15. 2025.
Anopheles stephensi, a major Asian malaria vector, is invading Africa and has been implicated in recent outbreaks of urban malaria. Control of this species is key to eliminating malaria in Africa. Genetic control strategies, and CRISPR/Cas9-based gene drives are emerging as ...
Stronger population suppression by gene drive targeting doublesex from dominant female-sterile resistance alleles
Tags: CRISPR, Gene drive, Population suppression, ResistanceWeizhe Chen, Ziye Wang, Jackson Champer, bioRxiv, 2025.
CRISPR homing drives can be used to suppress a population by targeting female fertility genes. They convert wild-type alleles to drive alleles in the germline of drive heterozygotes by homology-directed repair after DNA cleavage. However, resistance alleles produced by ...
An eco-epidemiological model for malaria with Microsporidia MB as bio-control agent
Tags: Anopheles, Modeling, Other Symbionts, Transmission distortionMfangnia CNT, Tonnang HEZ, Tsanou B, Keith Herren J, Modeling Earth Systems and Environment, 11. 2025.
Microsporidia MB is an endosymbiont which naturally infects Anopheles mosquitoes. Due to its ability to block Plasmodium transmission, it shows potential as a bio-based agent for the control of malaria. Its self-sustainability is promising, as it can spread through both ...
International perspectives on the meaning of engagement in biotechnology risk assessment: the case of gene drive
Tags: Gene drive, Risk assessment, Stakeholder engagementHartley, S., Stelmach, A., Kokotovich, A., & Smith, R. D. J., Journal of Risk Research, 2025.
Biotechnology remains challenging for risk assessors. The risk assessment of genetically modified organisms was the locus of considerable, acrimonious, and politicised debate and subjected to intense scrutiny. Since then, biotechnology has evolved to include new tools, such as ...
Mathematically modelling the population dynamics of CRISPR gene drive systems in the pine pest Sirex noctilio
Tags: CRISPR, Gene drive, Modeling, Pest management, Population genetics/dynamicsStrydom, H., Ouifki, R., Chapwanya, M., bioRxiv, 2025.
Sirex noctilio is an invasive pest of pine that has caused significant economic damage in South Africa and many other Southern Hemisphere countries. Current management tools are not efficient in all cases and consequently there is a need for more efficient and targeted control ...
Evolutionary consequences of long-distance dispersal in mosquitoes
Tags: Modeling, Mosquitoes, Population genetics/dynamicsThomas L Schmidt, Current Opinion in Insect Science, 68. 2025.
Long-distance dispersal (LDD) provides a means for mosquitoes to invade new regions and spread adaptive alleles, including those conferring insecticide resistance. Most LDD takes place on human transport vessels and will typically be rarer and more directionally constrained than ...
Applications and status of gene drive in plants
Tags: Ecology, Fruit fly, Invasive species, Population genetics/dynamics, Toxin-antidoteHay BA, PLOS Biology, 23. 2025.
Globalization—the movement of humans, plants, animals, and microbes—together with climate change, place numerous plant and animal species under novel stresses. For plants, threats include global warming, invasive species, weeds, animal pests, and vectors of disease. Harms can ...
Problem formulation for a small-scale field study of non-gene drive, genetically modified, male bias mosquitoes in Burkina Faso
Tags: Africa, Genetic biocontrol, Malaria, Risk assessment, Target malariaHayes, K. R., & Hosack, G. R., Human and Ecological Risk Assessment: An International Journal, 2025.
This article documents the problem formulation step of a risk assessment for a proposed small-scale field release in Burkina Faso of genetically modified (GM) An. coluzzii mosquitoes that carry a Paternal Male Bias (PMB) construct. These mosquitoes are part of the pathway ...
Synthetic Homing Endonuclease Gene Drives to Revolutionise Aedes aegypti Biocontrol – Game Changer or Pipe Dream?
Tags: Aedes, Gene drive synthetic, Vector controlJoshua X.D. Ang, Sebald A.N. Verkuijl, Michelle A.E. Anderson, Luke Alphey, Current Opinion in Insect Science, 2025.
The increasing burden of Aedes aegypti-borne diseases, particularly dengue, is a growing global concern, further exacerbated by climate change. Current control strategies have proven insufficient, necessitating novel approaches. Synthetic homing endonuclease gene (sHEG) drives ...
An innovation in host responses to escalating genomic conflicts
Tags: Fruit fly, Genomics, Selfish genetic elementsMartí, Emiliano et al., Trends in Genetics, 2025.
Conflicts between selfish elements and their hosts can trigger rapid structural and regulatory changes in genomes. Chen et al. discovered a novel species-specific innovation in response to a meiotic driver in Drosophila melanogaster. Their discovery highlights a new dimension in ...
Anticipating evolutionary responses of mosquito mating systems to population suppression with mass-reared males
Tags: Evolution, Modeling, Mosquitoes, Population suppressionBonsall, M.B., Cator, L.J., Current Opinion in Insect Science, 68. 2025.
Strategies that rely on the mass release of males to suppress mosquito populations will exert selective pressure on natural mating systems. Here, we investigate how mass releases might affect the mating behaviors of wild target populations. We highlight gaps in our understanding ...
Wolbachia: A bacterial weapon against dengue fever- a narrative review of risk factors for dengue fever outbreaks
Tags: Dengue, Risk and safety, WolbachiaSafaei, S., Derakhshan-Sefidi, M., Karimi, A., New Microbes and New Infections, 65. 2025.
Arboviruses constitute the largest known group of viruses and are responsible for various infections that impose significant socioeconomic burdens worldwide, particularly due to their link with insect-borne diseases. The increasing incidence of dengue fever in non-endemic regions ...
Comparison of oviposition and adult trapping to monitor wMel introgression for Wolbachia-based vector control
Tags: Aedes, Vector control, WolbachiaNelson, E., Pereira, T.N., Ribeiro E., et al., bioRxiv, 2025.
Wolbachia introgression into Aedes aegypti mosquito populations has been shown to be effective in preventing dengue and is being evaluated for WHO prequalification. Monitoring the long-term introgression of Wolbachia (wMel)-positive Aedes aegypti mosquitoes, however, requires ...
Mosquito Sex Separation using Complementation of Selectable Traits and Engineered Neo-Sex Chromosomes
Tags: Aedes, CRISPRZaada, D.S.Y., Toren, O., Krsticevic, F., et al., bioRxiv, 2025.
Effective and scalable sex separation remains a critical challenge for mosquito genetic control strategies. Genetic sexing strains (GSS) address this by genetically linking maleness with selectable traits, enabling efficient removal of females before release. Here, we describe a ...
A predatory gene drive for targeted control of self-transmissible plasmids
Tags: Gene drive, ModelingRyan Tsoi et al., Science Advances, 11. 2025.
Suppressing plasmid transfer in microbial communities has profound implications due to the role of horizontal gene transfer (HGT) in spreading and maintaining diverse functional traits such as metabolic functions, virulence factors, and antibiotic resistance. However, existing ...
Global asymptotic stability in a delay stage structured model for mosquito population suppression
Tags: Cytoplasmic incompatibility, Modeling, Population suppression, WolbachiaHuang, Mg., Yu, Js., Applied Mathematics, 40:112-136. 2025.
A promising avenue to control mosquito-borne diseases such as dengue, malaria, and Zika involves releasing male mosquitoes carrying the bacterium Wolbachia in wild areas to drive female sterility by a mechanism called cytoplasmic incompatibility (CI). In this work, we initiate ...
Exploiting Wolbachia as a Tool for Mosquito-Borne Disease Control: Pursuing Efficacy, Safety, and Sustainability
Tags: Arbovirus, Cytoplasmic incompatibility, Population modification/replacement, Stakeholder engagement, Vector control, WolbachiaMoretti, R., Lim, J. T., Ferreira, A. G. A., et al, Pathogens, 14:285. 2025.
Despite the application of control measures, mosquito-borne diseases continue to pose a serious threat to human health. In this context, exploiting Wolbachia, a common symbiotic bacterium in insects, may offer effective solutions to suppress vectors or reduce their competence in ...
Adjacent spillover efficacy of Wolbachia for control of dengue: emulation of a cluster randomised target trial
Tags: Asia, Dengue, Incompatible insect technique, WolbachiaLim, J.T., Mailepessov, D., Chong, C.S. et al., BMC Medicine, 23. 2025.
Matings between male Aedes aegypti mosquitoes infected with wAlbB strain of Wolbachia and wild-type females yield non-viable eggs, thereby suppressing Ae. aegypti abundance in the field. We evaluated the spillover efficacy of releasing wAlbB-infected Ae. aegypti male ...
Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi
Tags: Anopheles, CRISPR, Malaria, Population suppression, Sex distorterLarrosa-Godall, M., Ang, J.X.D., Leftwich, P.T. et al., Parasites & Vectors, 18. 2025.
Anopheles stephensi is a competent malaria vector mainly present in southern Asia and the Arabian Peninsula. Since 2012, it has invaded several countries of eastern Africa, creating an emerging risk of urban transmission. Urgent efforts are required to develop novel and more ...
Functional constraints of wtf killer meiotic drivers
Tags: Selfish genetic elements, Toxin-antidoteNidamangala Srinivasa A., Campbell S., Venkatesan S., et al., PLOS Genetics, 21. 2025.
Diploid organisms, such as humans, have two copies of most genes. Only one copy, however, is transmitted through gametes (e.g., sperm and egg) to any given offspring. Alternate copies of the same gene are expected to be equally represented in the gametes, resulting in random ...
Mark-Release-Recapture of Packed and Shipped Aedes aegypti with Wolbachia: Implications for Conducting Remote Incompatible Insect Technique Programs
Tags: Aedes, Incompatible insect technique, Population suppression, WolbachiaOhm, J. R., Lynd, A., McGowan, A., et al., The American Journal of Tropical Medicine and Hygiene, 2025.
Male mosquitoes containing the endosymbiont Wolbachia (Wb+) can be used as a tool to suppress wild mosquito populations through a technique termed incompatible insect technique (IIT). IIT programs reduce wild mosquitoes via incompatible matings between released males and wild ...
Gene drives. Technologies for spreading genetic modifications in populations. TAB-Fokus
Tags: Europe, Gene drive, Policy, Risk and safetyKönig, H., Kolleck, A., Sauter, A., TAB-Fokus, 48. 2025.
Gene drives have the potential to help solve major challenges, including the fight against invasive species or vector-borne diseases such as malaria. These hopes are offset by technical and scientific challenges as well as environmental risks. The policy brief TAB-Fokus no. 48 on ...
Engineering drive–selection balance for localized population suppression with neutral dynamics
Tags: CRISPR, Pest management, Population suppression, Toxin-antidoteWillis, K., and Burt, A., Proceedings of the National Academy of Sciences, 122. 2025.
While the release of sterile males has been highly successful in suppressing some pest populations, it is impractical for many species due to the males disappearing after a single generation, necessitating large, repeated releases to maintain sufficient impact. Synthetic gene ...
Gene drive: communication, hype, and the publics
Tags: Genetic engineering, Malaria, Stakeholder engagementBoëte, C., Journal of Medical Entomology, 2025.
Engineered gene drive (EGD) systems are probably the most high-tech approach considered for their potential role in the control of vector-borne diseases. Interestingly, the rhetoric around it often goes along with a negative presentation of the current “conventional” tools ...
wStri spread dynamics in Nilaparvata lugens via discrete mathematical models
Tags: Cytoplasmic incompatibility, Modeling, Other invertebrates, WolbachiaZheng, B., Yang, H., Elaydi, S. et al., Journal of Mathematical Biology, 90. 2025.
Wolbachia, an intracellular bacterium, is well-known for inducing cytoplasmic incompatibility, which has become a promising and environmentally sustainable strategy for controlling pest populations. The strain wStri, specifically identified in Nilaparvata lugens (brown ...
A comparative assessment of self-limiting genetic control strategies for population suppression
Tags: Population suppression, Self limiting, Sterile insect technique (SIT)Yue Han, Jackson Champer, Molecular Biology and Evolution, 2025.
Genetic control strategies are promising solutions for control of pest populations and invasive species. Methods utilizing repeated releases of males such as Sterile Insect Technique (SIT), Release of Insects carrying a Dominant Lethal (RIDL), self-limiting gene drives, and gene ...
CRISPR/Cas9 Genome Editing in the Diamondback Moth: Current Progress, Challenges, and Prospects
Tags: CRISPR, Gene drive, Genetic biocontrol, MothsAsad, M., Chang, Y., Liao, J., & Yang, G., International Journal of Molecular Sciences, 26:1515. 2025.
The development of site-specific genome-editing tools like CRISPR (clustered regularly interspaced short palindromic repeat) and its associated protein, Cas9, is revolutionizing genetic engineering with its highly efficient mechanism, offering the potential for effective pest ...
Engineering gene drive docking sites in a haplolethal locus in Anopheles gambiae
Tags: Anopheles, CRISPR, Gene drive, ResistanceAndrea L Smidler, Eryney A Marrogi, Sean Scot, et al., bioRxiv, 2025.
Gene drives are selfish genetic elements which promise to be powerful tools in the fight against vector-borne diseases such as malaria. We previously proposed population replacement gene drives designed to better withstand the evolution of resistance by homing through haplolethal ...
Reenacting a mouse genetic evolutionary arms race in yeast reveals that SLXL1/SLX compete with SLY1/2 for binding to Spindlins
Tags: Genetics, Rodents, X chromosome, Y-chromosomeM.F. Arlt,A.N. Kruger,C.M. Swanepoel,& J.L. Mueller, Proceedings of the National Academy of Sciences, 122. 2025.
In the house mouse, an evolutionary arms race between proteins encoded by the X-linked Slxl1/Slx and Y-linked Sly gene families during spermatogenesis can distort offspring sex ratio, but how these proteins compete remains unknown. We report how SLXL1/SLX competes with SLY1/SLY2 ...
RNA-guided nucleases enable a gene drive of insertion sequences in plasmids
Tags: Gene driveKepler S. Mears, Fernando W. Rossine, Natalia Quinones-Olvera, et al., bioRxiv, 2025.
Mobile genetic elements (MGEs) and the interactions between them are a major source of evolutionary innovation. Insertion sequences, the simplest MGEs usually encoding only the necessary genes for transposition and maintenance, are widespread in bacterial genomes, and are ...
Wolbachia-based mosquito control: Environmental perspectives on population suppression and replacement strategies
Tags: Ecology, Modeling, Population modification/replacement, Population suppression, WolbachiaBhattacharyya, J., Roelke, D.L., Acta Tropica, 262. 2025.
Mosquito-borne diseases pose a significant threat to global health, and traditional mosquito control methods often fall short of effectiveness. A promising alternative is the biological control strategy of transinfecting mosquitoes with Wolbachia, a bacterium capable of ...
Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease
Tags: Aedes, Anopheles, Arbovirus, Dengue, Toxin-antidoteFrench, S., Da Silva, R., Storm, J. et al., Parasites & Vectors, 18. 2025.
Mosquitoes are responsible for the transmission of numerous pathogens, including Plasmodium parasites, arboviruses and filarial worms. They pose a significant risk to public health with over 200 million cases of malaria per annum and approximately 4 billion people at risk of ...
Antagonistic kinesin-14s within a single chromosomal drive haplotype
Tags: Agriculture, Selfish genetic elementsMeghan J. Brady, Anjali Gupta, Jonathan I. Gent, et al., bioRxiv, 2025.
In maize, there are two meiotic drive systems that operate on large tandem repeat arrays called knobs that are found on chromosome arms. One meiotic drive haplotype, Abnormal chromosome 10 (Ab10), encodes two kinesin proteins that interact with two distinct tandem repeat arrays ...
Implications of successive blood feeding on Wolbachia-mediated dengue virus inhibition in Aedes aegypti mosquitoes
Tags: Aedes, Dengue, WolbachiaRebecca M. Johnson, Mallery I. Breban, Braiya L. Nolan, et al., bioRxiv, 2025.
Dengue virus (DENV) is a mosquito-borne virus that poses a continued and increasing threat to public health. A promising strategy to mitigate the burden of DENV is introgression of the virus-inhibiting Wolbachia pipientis bacterium into Aedes aegypti populations in the field. ...
Functional constraints of wtf killer meiotic drivers
Tags: Selfish genetic elements, Toxin-antidoteNidamangala Srinivasa A, Campbell S, Venkatesan S, et al., PLOS Genetics, 21. 2025.
Killer meiotic drivers are selfish DNA loci that sabotage the gametes that do not inherit them from a driver+/driver− heterozygote. These drivers often employ toxic proteins that target essential cellular functions to cause the destruction of driver− gametes. Identifying the ...
Small RNA-mediated suppression of sex chromosome meiotic conflicts during Drosophila male gametogenesis
Tags: Fruit fly, Sex distorterVedanayagam, J., Biochemical Society Transactions, 53:281-291. 2025.
Meiosis is an evolutionarily conserved process in eukaryotes that ensures equal segregation of alleles and chromosomes during reproduction. Although parity in allelic transmission is the norm, selfish genes such as meiotic drivers can violate Mendel’s first law of segregation. ...
Public attitudes to genetic technology for invasive pest control and preferences for engagement and information: a segmentation analysis
Tags: Genetic biocontrol, Pest management, Stakeholder engagementHobman E.V., Mankad A., Carter, L., Collins K., Frontiers in Bioengineering and Biotechnology, 12. 2025.
Advances in genetic technology hold promise in managing the increasing problem of invasive pests. The current study sought to improve our understanding of public perceptions, and potential public engagement pathways and information needs as the technology is researched and ...
Suppression of Aedes aegypti may not affect sympatric Aedes albopictus populations: findings from two years of entomological surveillance in Singapore
Tags: Aedes, Asia, WolbachiaWong, W.J., Tan, C.H., Verkaik, M.G. et al., Scientific Reports, 15:2253. 2025.
Globally, multiple trials have successfully demonstrated the effectiveness of novel tools, such as the sterile and incompatible insect techniques, in suppressing Aedes aegypti populations. However, there is concern that Aedes albopictus, another arbovirus-competent vector, may ...
Controlling the frequency dynamics of homing gene drives for intermediate outcomes
Tags: CRISPR, Modeling, ResistanceCamm B., Fournier-Level A., G3: Genes|Genomes|Genetics, 2025.
Gene drives have enormous potential for solving biological issues by forcing the spread of desired alleles through populations. However, to safeguard from the potentially irreversible consequences on natural populations, gene drives with intermediate outcomes that neither fixate ...
Generating sterile Anopheles mosquitoes to combat malaria transmission
Tags: Anopheles, Malaria, Sex distorter, Vector controlXu, X. and Champer, J., Research Communities by Springer Nature, 2025.
Malaria remains a deadly disease, claiming hundreds of thousands of lives worldwide every year. The primary vectors of malaria are Anopheles mosquitoes, including Anopheles gambiae and Anopheles stephensi. Controlling mosquito populations is crucial for stopping malaria ...
Establishment of pupal color as a screening marker and activity analysis of six U6 promoters in Zeugodacus cucurbitae using the white pupae gene
Tags: CRISPR, Genetic engineering, Pest managementFan Z., Wu Y., Zha X., Ma S., et al., Pest Management Science, 2025.
The genetic control method, which is environmentally friendly and species-specific, has effectively reduced or eliminated pests in many areas. One essential requirement to control a species is the identification of its genetic and molecular elements. Such elements, however, are ...
Upscaling irradiation protocols of Aedes albopictus pupae within an SIT program in Reunion Island
Tags: Aedes albopictus, Irradiation method, Reunion (France), Sterile insect technique, UpscaleLucie Marquereau, Hanano Yamada, David Damiens, Antonin Leclercq, Brice Derepas, Cécile Brengues , Brice William Dain , Quentin Lejarre 1, Mickael Proudhon , Jeremy Bouyer and Louis Clément Gouagna, Scientific Reports, 14:12117. 2025.
The implementation of the sterile insect technique against Aedes albopictus relies on many parameters, in particular on the success of the sterilization of males to be released into the target area in overflooding numbers to mate with wild females. Achieving consistent sterility ...
Life-history traits of a fluorescent Anopheles arabiensis genetic sexing strain introgressed into South African genomic background
Tags: COPAS, Malaria, South Africa, Sterile insect technique (SIT), Vector controlNonhlanhla L. Ntoyi, Thabo Mashatola, Jérémy Bouyer, Carina Kraupa, Hamidou Maiga, Wadaka Mamai, Nanwintoum, Bimbile‑Somda, Thomas Wallner, Danilo O. Carvalho, Givemore Munhenga and Hanano Yamada, Malaria Journal, 21. 2025.
South Africa has set a mandate to eliminate local malaria transmission by 2023. In pursuit of this objective a Sterile Insect Technique programme targeting the main vector Anopheles arabiensis is currently under development. Significant progress has been made towards ...
Animal trypanosomosis eliminated in a major livestock production region in Senegal following the eradication of a tsetse population
Tags: Case-control study, Eradication, Seroprevalence, Sterile insect technique, Sterile insect technique (SIT), TrypanosomeMomar Talla Seck, Assane Guèye Fall, Adji Marème Gaye, Geoffrey Gimonneau, Mamadou Ciss, Mame Thierno Bakhoum, Baba Sall, Mireille Djimangali Bassène1, Renaud Lancelot, Marc J.B., Vreysen, and Jérémy Bouyer, Parasite 31, 31. 2025.
African animal trypanosomosis (AAT) was one of the main disease-related constraints to the development of intensive livestock production systems in the Niayes region of Senegal, a 30 km wide strip of land along the coast between Dakar and Saint-Louis. To overcome this constraint, ...
Integrating malaria vaccine and CRISPR/Cas9 gene drive: a comprehensive strategy for accelerated malaria eradication
Tags: CRISPR, Gene drive, MalariaAbraham, I.C., Aboje, J.E., Ukoaka, B.M. et al., Malaria Journal, 24. 2025.
Malaria remains a significant public health challenge, particularly in low- and middle-income countries, despite ongoing efforts to eradicate the disease. Recent advancements, including the rollout of malaria vaccines, such as RTS,S/AS01 and R21/Matrix-M™, offer new avenues for ...
Gene drive-based population suppression in the malaria vector Anopheles stephensi
Tags: CRISPR, Genetic engineering, Population suppressionXu, X., Chen, J., Wang, Y. et al., Nature Communications, 16:1007. 2025.
Gene drives are alleles that can bias the inheritance of specific traits in target populations for the purpose of modification or suppression. Here, we construct a homing suppression drive in the major urban malaria vector Anopheles stephensi targeting the female-specific exon of ...
Assessing Radiation-Induced Enzyme Activation in Aedes aegypti: Potential Challenges for SIT-Based Vector Management
Tags: Aedes, Sterile insect technique (SIT), Vector controlEdvane Borges da Silva, Sloana Giesta Lemos Florêncio, Ademir Amaral, et al., Acta Tropica, 261. 2025.
This study characterizes the Aedes aegypti population from Fernando de Noronha Island, Pernambuco, Brazil, prior to implementing the Sterile Insect Technique (SIT). The main objective was to assess changes in glutathione S-transferase (GST) enzyme activity, previously linked to ...
A comprehensive review of biological and genetic control approaches for leishmaniasis vector sand flies; emphasis towards promoting tools for integrated vector management
Tags: Genetic engineering, Other arthropods, Vector controlKumari, Y., Gunathilaka, N., Amarasinghe, D., PLOS Neglected Tropical Diseases, 19. 2025.
Leishmaniasis is a health problem in many regions with poor health and poor life resources. According to the World Health Organization (WHO), an estimated 700,000–1 million new cases arise annually. Effective control of sand fly vector populations is crucial for reducing the ...
Assessment of drive efficiency and resistance allele formation of a homing gene drive in the mosquito Aedes aegypti
Tags: Aedes, CRISPR, Gene drive, Mosquitoes, Vector controlYang, X., Xu, X., Chen, Y. et al., Journal of Pest Science, 2025.
Aedes aegypti, known for transmitting viruses such as dengue, Zika and yellow fever, poses a significant public health threat. Conventional insecticides give rise to a range of issues, including ecological contamination and insect resistance. Hence, there is a pressing demand for ...
