Keywords: Video

Gene Drive Variations – BJC Submission

35129
Matt Lambie,  YouTube,  2025-09-12 11:06:14.

Nature goes inside the world’s largest ‘mosquito factory’ — here’s the buzz

35120
Adam Levy & Mariana Lenharo,  Nature,  2025-09-08 08:31:27.
Raising mosquitoes to tackle disease might sound like an odd concept, but that’s what a facility in Brazil is aiming to do. Millions of mosquitoes are produced there every week, but these insects carry harmless Wolbachia bacteria that curbs their ability to spread deadly human viruses. Nature reporter Mariana Lenharo visited the facility and told us all about her experience in this Podcast Extra.

Ecology and evolution in gene drive modeling

35060
NSF-Simons NITMB,  YouTube,  2025-08-25 16:09:18.
Speaker: Gili Greenbaum Title: Ecology and evolution in gene drive modeling This talk was recorded as part of the Modeling and Theory in Population Biology workshop at NITMB. The NSF-Simons National Institute for Theory and Mathematics in Biology (NITMB) aims to integrate the disciplines of mathematics and biology in order to transform the practice of biological research and to inspire new mathematical discoveries. NITMB is a partnership between Northwestern University and the University of Chicago. It is funded by the National Science Foundation DMS-2235451 and the Simons Foundations MP-TMPS-00005320. The mission of the NITMB is to create a nationwide collaborative research community that will generate new mathematical results and uncover the “rules of life” through theories, data-informed mathematical models, and computational and statistical tools. The NITMB leverages close collaborations between experimentalists and theorists to synergize discovery. The fundamental research done by NITMB will stimulate advances in areas as diverse as the environment, medicine, and technology development. NITMB members and visitors share space in downtown Chicago that is readily accessible to collaborators across the U.S. and the world. NITMB uses an interlocking set of strategies and initiatives aimed at broad impacts for the mathematical and biological research communities. Targeted research bringing together mathematicians and biologists to collaborate and train the next generation of interdisciplinary scientists. Scientific long programs, workshops, and conferences enhancing collaboration between mathematics and biology. An innovative research program organized around five interrelated themes, selected because they reflect key capabilities of biological systems and interconnect with open mathematical problems.


Importation of the non gene drive male bias mosquito to Uganda

34926
Target Malaria,  YouTube,  2025-06-23 14:55:08.
This video documents the importation of non gene drive male bias mosquitoes by Target Malaria’s team in Uganda. The video follows the journey from Entebbe Airport to the Arthropod Containment Level 2 (ACL2) insectary at the Uganda Virus Research Institute, highlighting key moments such as interviews with project staff and stakeholders—including regulatory officials and members of the community consultative group. It also captures the process of unpacking the eggs from the secure packaging and transferring them to the larval trays. Produced in both English and Luganda, this video is designed for project stakeholders, supporting presentations and other communication efforts to keep communities and partners informed about the project’s activities in Uganda.

Gene Drive Mosquitoes: Can We End Malaria?

34930
The Curious Scholarette,  YouTube,  2025-06-19 14:56:01.
What if we could genetically modify mosquitoes to stop malaria in its tracks? In this episode of The Curious Scholarette, we explore the groundbreaking world of gene-drive technology — a powerful tool that could eliminate malaria-carrying mosquitoes by altering their DNA. But with great power comes great ethical debate. 🔬 In this video, we break down: What gene drives are and how they work How scientists are using CRISPR to disrupt mosquito reproduction or malaria transmission Evidence from field trials and lab experiments The potential risks: ecological disruption, irreversible changes, and bioethical concerns Perspectives from global health experts, bioethicists, and community leaders 📍 Why it matters: Malaria kills over 600,000 people each year, mostly in sub-Saharan Africa. Could gene-drive mosquitoes be the silver bullet? Or are we playing with fire? 🧪 Sources Cited: WHO Malaria Report

Status of gene drive research in Africa; Ifakara Health Institute

34941
African Genetic Biocontrol Consortium,  YouTube,  2025-06-16 08:56:50.
The African Genetic Biocontrol Consortium is an agreement established by not-for-profit member organizations based in Africa with a vision to build an informed local leadership to support the requirements for development, decision-making and on the utility of genetic biocontrol technologies for animal, public health, and conservation in Africa. To fulfil this vision the Consortium has established a Forum for Institutional Committees in Africa (IBC - Africa Forum) to provide a platform for interaction among African experts and institutions to enhance opportunities for technical capacity strengthening, knowledge exchange and deliberation about the challenges and opportunities of genetic biocontrol technologies for the public good, which will amplify African influence on their development and provide critical input for decision-making by product developers, policy makers, and other stakeholders. An Institutional Biosafety Committee (IBC) is a committee created in an Institution in accordance with the Biosafety law or regulation in a Country. The IBC reviews, approves and oversees research involving the use of genetically modified organisms (GMOs), recombinant or synthetic DNA/RNA and other biohazards. The IBC assists the Principal Investigator, supervisors, funders, and the Biosafety Regulators with obtaining proper authorization for their studies. The Committee also approves procedures for procurement, use, storage, transportation, and disposal of bio-hazardous material.

Global and regional updates on gene drive governance; AUDA-NEPAD update on regional work

34860
African Genetic Biocontrol Consortium,  YouTube,  2025-05-26 21:04:00.
AUDA-NEPAD update on regional work. Presentation on AUDA-NEPAD’s initiatives and progress in governance and capacity-building efforts related to synthetic biology, particularly on gene drives.

Inside the lab breeding malaria resistant GM mosquitoes

34618
Reuters,  YouTube,  2025-03-18 12:02:59.
An international team of scientists are developing genetically modified mosquitoes that can slowly convert the entire wild population of mosquitoes resistant to transmitting malaria, the world’s most deadly disease.

What Is Gene Drive? – Biology For Everyone

34607
Biology for Everyone,  YouTube,  2025-03-18 11:07:30.
What Is Gene Drive? In this informative video, we will introduce you to the intriguing concept of gene drive, a revolutionary technology that enables the rapid transmission of specific traits within a species. We will break down the mechanics of how gene drive works, including the role of genetic engineering tools like CRISPR-Cas9. You will learn about the process of inserting a gene drive into an organism's DNA and how it ensures that the desired genes are passed on to nearly all offspring. We'll also discuss the various applications of gene drives, including their potential to combat insect-borne diseases such as malaria, dengue, and Zika, as well as their use in managing invasive species and addressing pesticide resistance. Additionally, we will explore the different types of gene drives, such as homing-based gene drives and sex distorter drives, and how these methods can impact populations. While the potential of gene drives is exciting, we will also touch on the associated risks and the importance of careful management to prevent unintended consequences. Join us for this engaging discussion, and subscribe to our channel for more enlightening content on biology and genetic technologies.

What are the evolutionary considerations of rodent gene drives for conservation and human health?

34662
Triangle Center for Evolutionary Medicine,  YouTube,  2025-02-21 09:38:19.
Biodiversity, human health, and food security can all be impacted by invasive rodents. These negative impacts are particularly seen on islands, where rodent eradications with traditional methods can sometimes fail due to evolutionary resistance. Gene drives may offer an approach to the challenge of rodent eradication on islands. My primary research focus is wild house mice (Mus musculus) and the potential use of gene drive technology. Mus are a key genetic model system and an invasive species on many islands worldwide. Evolutionarily sound approaches are needed, and we are investigating ways to tailor genetic techniques to unique island populations. Using models on gene drive mice can help us predict how laboratory/wild mice would introgress into a population. Evolutionary resistance is also possible; the mice may evade our best methods. However, gene drive technology in rodents can potentially produce significant gains for conservation and society. To this end, a broad interdisciplinary lens with many differing perspectives is required.

Genetically modified mosquitoes could combat deadly diseases, scientists say

34255
The Sydney Morning Herald,  2025-01-13 15:25:27.
Genetically modified mosquitoes could be the solution to stopping deadly diseases spread by mosquito bites, scientists say.

TWiV 1161: Baby you can drive my gene

33394
MicrobeTV,  YouTube,  2024-11-04 17:40:40.
TWiV reviews continuing expansion of poliovirus type 2, removal of influenza B/Yamagata from the vaccine, Nobel Prize for miRNAs, protective immune response with a adenovirus-associated virus vector expressing a computationally designed hemagglutinin, and viral gene drive during herpes simplex 1 infection in mice.

GeneConvene Global Collaborative | Considerations for the First Field Trials of Gene Drive for Malaria

33388
GeneConvene Global Collaborative,  YouTube,  2024-11-04 17:19:36.
A webinar organized by the GeneConvene Global Collaborative discussed the potential first field trials of gene drive technology for malaria control. This genetic modification approach aims to alter mosquito populations to reduce their ability to transmit malaria. While laboratory results are promising, no field trials have been conducted yet. Experts convened to explore key considerations for trial design, including efficacy, safety, and stakeholder perceptions. The challenges of indefinite spread associated with low-threshold gene drives complicate trial logistics, necessitating a phased testing approach recommended by the WHO. Key factors for site selection include regulatory structures, existing health data, and the need for isolated mosquito populations. The session aimed to share insights and foster discussion on the future of gene drive applications in malaria control.

Why are gene drive technologies being considered to help restore biodiversity on islands?

32530
Outreach Network for Gene Drive Research,  2024-10-15 11:55:45.
Researchers have been studying how to harness gene drives to solve some of society’s most intractable problems for a long time. Public health and ecosystem conservation are two of the main areas where research has focused, although other uses are also possible.

How to Use Genetic Biocontrol to Manage Insect Pests

29891
Scientific Animations Without Borders,  YouTube,  2024-05-07 16:41:35.
Pest insects often transmit disease to humans and animals and destroy crops. Controlling these pests can improve human health and increase agricultural production. Pest insects are often controlled by releasing other insects into the environment that will specifically kill the pests. This method of pest control is called biological control and is environmentally friendly because it reduces reliance on chemical insecticides and targets only the pest insects. Genetic biocontrol is a type of biological control where the released insects are the same species as the pest but with critical genetic differences and traits that affect their reproduction or lifespan.

SPOTLIGHT: Gene Drives for Malaria Elimination in Africa

28916
Ifakara Health Institute,  YouTube,  2024-02-20 20:05:51.
This SPOTLIGHT Series features Dr. Marceline Finda, a distinguished Research Scientist at Ifakara Health Institute. The insightful 20-minute discussion centered around the topic: "Gene Drives for Malaria Elimination in Africa."

Gene Drives: Mechanisms and Key Research, Explained

28795
Julia Bauman,  60 Second Science,  2024-01-15 16:59:40.
A technical primer on CRISPR-based gene drives, which hold massive potential for mitigating the harms invoked by some species. We cover what a gene drive is, how it works at the genetic level, and summarize key safety & efficiency features developed in recent years.

ISAAA Inc. | Genetic Tools For Conservation and Health: What’s The Role of Gene Drives?

28634
Kristine Grace N. Tome,  Science Speaks,  2023-12-04 11:20:10.
ISAAA Inc., in partnership with the Outreach Network for Gene Drive Research and the Malaysian Biotechnology Information Centre (MABIC), gathered approximately 834 online participants during the webinar Genetic Tools for Conservation and Health: What's the Role of Gene Drives? held on November 16, 2023, via Zoom and livestreamed on Facebook and YouTube. The online session is the first of the 2023 Gene Drive Webinar Series that focuses on the interests of specific countries and aims to promote a productive and balanced conversation on the benefits and risks of possible gene drive applications relevant to national priorities. The Philippines has been picked as the first country to be engaged in the webinar series. The Philippines has been at the forefront of biotechnology research and regulation in Asia for a long time and plays an important role in shaping the region’s views on novel technologies and developing expertise.

Regulation of gene drive technologies for malaria control & elimination

33083
Ifakara Health Institute,  2023-05-16 13:15:08.
The video talks about the importance of ensuring effective and thoughtful community and stakeholder engagement throughout research, development and deployment of gene drives for malaria control.

Biotechnology and Biosafety in the Biodiversity Convention and its Protocols

33000
GeneConvene Global Collaborative,  2022-04-23 09:35:50.
Dr. Piet van der Meer provides a clear exposition of the history of the Convention on Biological Diversity and puts in the the broader context of the development of biotechnology beginning with the first recombinant DNA containing organisms in 1972. He also describes and explains how the CBD is governed, its procedures and its relationship to current biosafety frameworks.


How do local communities participate in gene drive research?

16680
Outreach Network for Gene Drive Research,  2021-04-12 14:39:00.
How do local communities participate in gene drive research?

ARRIGE 2020 Meeting | The promise of CRISPR and gene drive systems to end malaria in Africa

15145
E. Gomez-Diaz,  ARRIGE org,  2020-11-16 17:08:32.
Presentation by Elena Gómez Díaz (IPBLN-CSIC, Granada, Spain) at the ARRIGE 2020 meeting on "The promise of CRISPR and gene drive systems to end malaria in Africa". Discussion is included at the end of the Ruud de Maagd presentation.https://youtu.be/te3MJ8EZoes

Regional Development of Regulatory Policies on Gene Drives and Risk Assessment

33090
GeneConvene Virtual Institute,  2020-10-28 13:30:07.
In this Webinar Dr. Martin Lema discusses how well biosafety regulatory frameworks in Latin America can accommodate new genetic technologies such as Gene Drive.

Overview of Regulatory Frameworks Covering Gene Drives Oct 21 2020

33087
GeneConvene Virtual Institute,  2020-10-26 13:25:57.
These are two webinars presented around the topic of an Overview of Regulatory Frameworks Covering Gene Drives. The presenters were Ms. Wadzi Mandivenyi from the Convention on Biological Diversity and Dr. Marion Law from the World Health Organization. These presentations were given on October 21, 2020.

GeneConvene Global Collaborative Webinar Series | Gene Drive Policy and Regulatory Considerations 2020

14677
Hector Quemada and David O'Brochta,  GeneConvene Global Collaborative,  2020-10-13 17:50:24.
This is series of webinars the regulatory and policy challenges of moving new innovative genetic biocontrol products such as gene drive technologies to the field will be featured.

GeneConvene Global Collaborative Webinar Series | Gene Drive Policy and Regulatory Consideration

14670
Hector Quemada and David O'Brochta,  GeneConvene Global Collaborative,  2020-10-13 17:34:35.
This is series of webinars the regulatory and policy challenges of moving new innovative genetic biocontrol products such as gene drive technologies to the field will be featured.

What are gene drives about?

7377
EFSAchannel,  2020-02-17 14:39:25.
EFSA expert Les Firbank, specialised in sustainable agriculture, talks about gene drives. Recent development in molecular biology are allowing scientists to engineer gene drives and use them to push desirable genes into target populations. How does that work? Learn more about this topic on in our new video.

Davos 2020 World Economic Forum | When Humankind Overrides Evolution

6813
M. Skipper,  World Economic Forum,  Davos 2020. 2020-01-21 15:32:08.
Advances in synthetic biology and other novel genetic procedures could resurrect extinct species or eliminate dangerous pests. What actions are needed now to ensure the ethical and responsible application of new genetic techniques?

Vereinigung Deutscher Wissenschaftler e.V. | Gene Drive Symposium-Critical Science Switzerland

6674
Critical Scientists Switzerland; European Network of Scientists for Social and Environmental Responsibility; Vereinigung Deutscher Wissenschaftler,  2019-05-24 18:26:07.

Gene Editing: Last Week Tonight with John Oliver (HBO)

6882
J. Oliver,  HBO,  2018-07-01 20:40:49.
Scientists are developing new ways to alter the genetic code of living organisms. John Oliver explores the risks, rewards, and wolf-related hazards of gene editing.

The Sterile Insect Technique

27105
IAEA/FAO,  2015-08-14 10:52:33.
For over 50 years, the Sterile Insect Technique (SIT) has been successfully used around the world to tackle pests that destroy fruit and kill livestock. The method uses radiation to sterilize male flies, which are mass-produced in rearing facilities. Large numbers of sterile males are released into a target area, where they mate with wild females. No offspring are produced, and the wild fly population declines over time. Once established, this technique provides sustainable, cost-effective and environmentally-friendly insect control.